PREVENTION

This study tests a clinical decision support tool that reminds doctors to follow CDC guidelines when reducing opioid doses in patients. About 200,000 primary care patients will be included. The goal is to lower the risk of withdrawal, overdose, and poisoning by encouraging safer …

This study tests ways to help more Black women get PrEP, a daily pill that prevents HIV. Researchers will work with 250 women at Planned Parenthood clinics in Illinois who have had a sexually transmitted infection. The goal is to make it easier for them to get a PrEP prescription…

This study compares a new 7-day pack of a nutrient supplement (SQ-LNS) to the usual daily packets for preventing malnutrition in children aged 6-22 months in Ethiopia. Researchers want to see if families use the weekly pack correctly and if it is as safe and easy to use. The goal…

This study tests two smartphone app programs designed to prevent anxiety and depression in adults who do not currently have these conditions. About 2,600 participants from Spain and Chile will use the app for one year. The goal is to see if personalized tips and tracking can redu…

This study tests whether taking a daily antiviral pill (acyclovir) can prevent herpes simplex outbreaks in people with autoimmune rheumatic diseases like lupus or rheumatoid arthritis. About 62 participants will receive either the drug or a placebo for 12 months, then be monitore…

This study tests whether a cold plasma treatment applied during groin surgery can prevent wound healing complications in high-risk patients with peripheral artery disease. About 214 participants will receive either the real plasma or a placebo device during their operation. Resea…

This study tests a program designed to improve well-being and prevent mental health issues in children aged 8-10 and their families. Over 15,000 participants across four European countries will take part in school-based activities and parent training. The goal is to see if these …

This study tests whether a smartphone app called 'Better Pregnancy,' powered by artificial intelligence, can help prevent gestational diabetes in pregnant women who are at high risk. About 400 women will either use the app plus receive standard prenatal care, or receive standard …

This study aims to improve an existing youth violence prevention program by adding content that directly addresses firearm-related risks, such as gun carrying and safe storage. Researchers will work with 45 teens aged 13-17 who are at high risk for firearm injury, along with thei…

This study tests a new approach to delivering the SafeCare program, which helps parents prevent child maltreatment. Researchers will work with 12 home visiting providers and 40 caregivers to see if a mix of in-person and virtual sessions can reach more families and improve parent…

This study looks at how to help VA medical centers better serve women Veterans, especially those in midlife. Researchers will test two different strategies to get more women involved in programs for heart health, weight management, and stress. The study involves 18 VA sites and f…

This study looks at a program called ezParent, which combines online training with group video sessions, to help parents of children aged 2 to 5. About 516 parents will take surveys at the start, and again after 10 and 24 weeks. The goal is to see if the program improves parentin…