PREVENTION

This study looks at how well different two-step cervical cancer screening methods work in Botswana, using an HPV test first. About 3,000 women aged 25 and older will take part, including those living with HIV. The goal is to find the most accurate and affordable way to catch earl…

This study tests a treatment called Diamyd® in children aged 8 to 17 who are at high risk for type 1 diabetes. The goal is to see if giving the drug directly into lymph nodes is safe and can prevent or delay the disease. Only 5 children with specific genetic markers are taking pa…

This study tests whether a digital platform called ToBrainHealth can help people aged 40-75 adopt and stick to brain-healthy habits like exercise, better sleep, and social activities. 120 volunteers will be split into three groups: one gets general advice, another gets personaliz…

This study looks at how to help VA medical centers offer virtual programs that prevent heart disease, diabetes, and depression in women Veterans. It involves 20 VA sites across 4 regions, testing two different support strategies. The goal is to see which approach gets more women …

This study tests whether proactive telemedicine (brief remote coaching on habits like smoking, diet, and exercise) works as well as in-person visits for rural adults who haven't seen their primary care team in over a year. About 120 participants will be randomly assigned to eithe…