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Heart CT Follow-Up could cut heart attacks in Non-Obstructive disease

NCT ID NCT06843005

Disease control Sponsor: Zhang longjiang,MD Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether doing a follow-up CT scan of the heart arteries in people with non-obstructive coronary artery disease can help doctors adjust treatment to better control cholesterol and prevent heart attacks, strokes, or death. About 3,100 participants will be randomly assigned to either standard care or care guided by the CT scan results. The goal is to see if this imaging-based strategy improves outcomes over three years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Coronary Computed Tomography Angiography (CCTA) scan
What this could lead to
If successful, this approach could help doctors personalize heart disease treatment based on plaque changes seen on CT scans, potentially reducing heart attacks and strokes.
What could go wrong
This is a large but early-stage study testing a management strategy, not a new drug. The benefit may be small, and the extra scans could lead to unnecessary procedures or anxiety.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 3,100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18 and 80 years old; 2. Known patients with non-obstructive coronary artery disease (disease duration ≥2 years); 3. Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations. Exclusion Criteria: 1. Patients who have experienced ACS or PCI/CABG; 2. Patients who have experienced adverse cardiovascular and cerebrovascular events; 3. Patients who have undergone follow-up CCTA or DSA examinations before enrollment; 4. Patients with severe hepatic and renal dysfunction; 5. Patients with contraindications to CCTA examinations; 6. Patients with poor initial CCTA image quality or data loss.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder nonobstructive coronary artery disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease (CAD) CT angiography Major adverse cardiovascular events (MACE) Prevention

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Research Institute Of Medical Imaging Jinling Hospital

    RECRUITING

    Nanjing, Jiangsu, 210018, China

More trials for these conditions

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