Post operative pain

Researchers are testing whether a nerve block using Exparel controls pain better than the standard bupivacaine block in adults having 1 to 3 level lumbar spinal fusion surgery. The trial enrolls 76 patients and measures pain scores, opioid use, hospital stay, and how quickly pati…

This study compares two schedules for taking non-opioid pain relievers (acetaminophen and NSAIDs) after a cesarean delivery: taking them at different times (staggered) or at the same time (simultaneous). The goal is to see which approach better controls pain and reduces the need …

This trial asks whether using sodium hypochlorite or saline to rinse the tooth, with or without cold therapy (cryotherapy), can reduce pain after a pulpotomy in permanent molars. Adults aged 15-40 with symptomatic irreversible pulpitis will undergo the procedure, and their pain w…

This study planned to compare two approaches for managing pain after shoulder surgery: neurofeedback training (a technique that teaches you to control your brain activity) and a standard pain management program. The goal was to see which method better reduces pain, improves shoul…

This study tests whether a nerve block (bilateral superficial cervical plexus block) plus local anesthetic can reduce pain, nausea, and opioid use after thyroid surgery. 74 adults having a partial or total thyroid removal are randomly assigned to receive either the nerve block or…

This study aimed to see if freezing certain nerves during minimally invasive heart surgery could lower pain afterward. It planned to enroll adults having mitral valve or atrial septal defect repair. However, the trial was withdrawn before any participants were enrolled, so no dat…

This study compares two pain management approaches after total knee or hip replacement: a combination of tramadol and oxycodone versus oxycodone alone. The goal is to see if the combination reduces the total amount of opioids needed and improves pain control with fewer side effec…

This early-stage trial tests whether adding either dexamethasone or dexmedetomidine to the numbing drug bupivacaine can improve pain control after rhinoplasty (nose job). The study will enroll 90 adults undergoing nose surgery. The main goal is to see how long it takes before pat…

This study aimed to see if a tiny dose of buprenorphine/naloxone (a medicine used for opioid addiction) could help control pain after surgery in people who already take strong painkillers. It was designed for adults having orthopedic or general surgery. However, the study was wit…

This study tests whether freezing specific nerves around the knee before total knee replacement surgery can reduce pain and the need for opioids afterward. One hundred adults scheduled for knee replacement will either receive the nerve-freezing treatment or a sham procedure. The …

This study tests two different pastes placed inside the tooth between root canal visits to see which one reduces pain and helps the bone heal better. Eighty adults with infected but painless front teeth will receive either Bio-C Temp or Metapaste. Pain is tracked for a week, and …

This study looks at how well women recover after mastectomy surgery. Some women receive a PECS nerve block with a long-lasting painkiller, while others do not. Researchers want to see if the block leads to better pain control and recovery quality 72 hours after surgery. About 800…