Freeze your pain away: new knee surgery trick cuts opioid use
NCT ID NCT05840276
First seen Jan 07, 2026 · Last updated May 22, 2026 · Updated 17 times
Summary
This study tests a treatment called cryoneurolysis, which freezes nerves around the knee before total knee replacement surgery. The goal is to reduce pain and the need for strong painkillers (opioids) after surgery. About 100 adults with knee osteoarthritis will be randomly assigned to receive either the real freezing treatment or a sham (fake) procedure before their surgery. Researchers will measure opioid use and pain levels for up to 6 months after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hospital of Southwest Jutland
Esbjerg, Region Syddanmark, 6700, Denmark
Conditions
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