PEDIATRIC

This study tested the safety and how the body processes a medication called lumateperone in teenagers with schizophrenia or schizoaffective disorder. It involved 26 participants aged 13 to 17. The main goal was to understand the drug's side effects and how it moves through the bo…

This study compared two procedures for removing dense kidney stones in children aged 2 to 12. One hundred children were randomly assigned to receive either a minimally invasive surgery (mini-PNL) or a non-invasive shockwave treatment (SWL). The main goal was to see which method w…

This study tested a new AI tool designed to measure fat in the liver using standard ultrasound images. It involved 50 children and teenagers with or suspected of having fatty liver disease. The goal was to see if the AI's measurements matched the results from a more complex and e…

This study compared three different sedative medicines given by mouth to children before hernia surgery. Researchers wanted to see which medicine worked best to help children feel calm and comfortable before their operation. The study involved 60 children aged 3-7 years who recei…

This study tested whether a nerve block could help children having surgery to create dialysis access feel less pain and need fewer strong opioid painkillers. Researchers compared 50 children aged 6 to 18 who received the nerve block during surgery to those who did not. The goal w…

This study tested whether a specific nerve block could help children with spastic cerebral palsy need less opioid pain medication after a major leg surgery. Researchers compared pain levels and medication use in 30 children who received the nerve block during surgery versus stand…

This study tested a special kit designed to make it easier and less painful to place an IV in young children. Researchers compared different combinations of a vein-finding device and a special catheter in 800 children aged 1 to 6. The main goals were to see if the kit improved th…

This study aimed to see if using an electronic device to measure a tooth's root canal causes less pain after treatment in children compared to the standard method using digital X-rays. Researchers treated 130 children aged 10-15 who needed a root canal and randomly assigned them …

This study aimed to better understand how a young child's brain is affected during major heart surgery. Researchers observed 15 children, aged 6 to 36 months, while they were under anesthesia for open-heart surgery. They used special sensors on the forehead to measure brain oxyge…