PANCREAS CANCER

This study tested a personalized vaccine made from each patient's unique cancer mutations (neoantigens) in people with pancreatic cancer. The vaccine was given after chemotherapy and before or after surgery to see if it is safe and boosts the immune system. 33 patients took part …

This early-stage study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle version of a chemotherapy agent, given through an IV, and the m…

This study tested whether combining two drugs—pembrolizumab (an immunotherapy) and azacitidine (a drug that affects gene activity)—could help people with advanced pancreatic cancer whose first treatment stopped working. About 36 adults with this cancer took part. The goal was to …

This study tested a new treatment plan for people with advanced pancreatic cancer that has spread. It combined chemotherapy with drugs that change how genes work and boost the immune system. The goal was to see if the combination is safe and can help control the cancer. 75 patien…

This study tested whether two oral chemotherapy drugs, vemurafenib and sorafenib, could help people with advanced pancreatic cancer that has a specific gene change (KRAS mutation) and has stopped responding to standard treatments. Ten participants took the drug combination to see…

This study tested two common antibiotics, cefoxitin and piperacillin-tazobactam, to see which one better prevents surgical site infections after a complex pancreatic surgery called pancreatoduodenectomy. Nearly 1,000 adults having this surgery took part. The goal was to find the …

This early-phase study tested whether adding the drug anakinra to standard chemotherapy is safe for people with advanced pancreatic cancer that has spread. Thirteen adults with metastatic pancreatic cancer took part. The main goal was to check for side effects, and researchers al…

This study tested a home monitoring system for people with advanced pancreatic cancer receiving a strong chemotherapy called FOLFIRINOX. The system tracked symptoms, weight, sleep, and activity to catch early warning signs of side effects. The goal was to reduce emergency hospita…

This study looked at whether it is safe and possible to grow mini-tumors (organoids) from pancreatic cancer samples in the lab. 60 patients with pancreatic cancer provided tumor tissue during surgery or biopsy. Researchers then tested different chemotherapy drugs on these organoi…

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …