PAIN

This study tested an experimental drug called GSK3858279 in 147 adults with long-term nerve pain caused by diabetes. The goal was to see if the drug could reduce daily pain better than a placebo. The trial was stopped early, so final results are limited, but the data may still he…

This study tested an experimental drug called GSK3858279 in 314 adults with moderate to severe knee osteoarthritis pain. The goal was to find the safest and most effective dose to reduce pain. The study was terminated early, but results may still help guide future research.

This small, early-phase trial tested whether taking ibuprofen (a pain reliever) and ondansetron (an anti-nausea drug) before a medical abortion could reduce side effects and improve patient satisfaction. The study enrolled 8 healthy women undergoing abortion up to 70 days of preg…

This study tested whether a 3D ultrasound device (Accuro) helps place epidurals more easily in obese pregnant women compared to the standard blind method. The trial planned to enroll 40 women with a BMI of 40 or higher who requested pain relief during labor. The study was termina…

This study tested whether D-cycloserine, a drug that affects brain signaling, could reduce pain in people with chronic low back pain lasting at least 6 months. About 203 adults with moderate to severe pain were to receive either the drug or a placebo. The study was terminated ear…

This study looked at whether cancer patients already taking strong opioids (like morphine) can stop taking paracetamol without their pain getting worse. Only 7 people took part before the study was stopped early. The goal was to see if paracetamol adds any extra benefit for pain …

This study looked at whether measuring heart rate patterns or skin responses can reliably show pain in premature babies, compared to a standard behavioral scale. Researchers enrolled 91 preterm newborns in a hospital setting. The goal was to find a more objective way to assess pa…

This study tested a virtual reality training program for healthcare teams to reduce disparities in maternal care. It involved 66 participants, including healthcare workers and new mothers. The goal was to see if the training could lower severe postpartum pain and improve respectf…