OVARIAN CARCINOMA

This early-stage trial tested a new personalized immunotherapy called TG4050 in 64 women with advanced ovarian, fallopian tube, or peritoneal cancer. All participants had completed standard chemotherapy and were in complete remission. The main goal was to check the treatment's sa…

This study tested a new drug (TJ004309) combined with an approved immunotherapy (atezolizumab) in 25 people with advanced ovarian, head and neck, lung, gastrointestinal, or triple-negative breast cancers. The goal was to see if the combination could shrink tumors. Participants ha…

This study tested whether adding an experimental drug (MK-4830) to standard chemotherapy and immunotherapy (pembrolizumab) could better reduce tumor DNA in the blood of people with advanced ovarian cancer. 160 participants received treatment before surgery. The goal was to see if…

This study tested a combination of two drugs, pamiparib and surufatinib, in 29 women with ovarian cancer that had stopped responding to platinum chemotherapy and had already been treated with a PARP inhibitor. The goal was to see if the combo could slow or stop cancer growth. The…

This early-phase trial tested a combination of two drugs, sapanisertib and ziv-aflibercept, in 83 adults with advanced solid tumors that had spread or could not be removed by surgery. The main goal was to find the safest dose and identify side effects. The approach aims to slow t…

This early-phase trial tested a combination of two drugs—trabectedin and durvalumab—in 40 people with advanced soft-tissue sarcoma or ovarian cancer that had not responded to prior treatments. The main goal was to find the safest dose and check for early signs of tumor shrinkage.…

This study tested whether bupropion, a medication often used for depression, can improve low sexual desire in women who have had breast or gynecologic cancer. About 230 women took either bupropion or a placebo pill for 9 weeks. The goal was to see if the drug could safely boost d…

This study looked at whether saliva samples can be used to remotely monitor cytomegalovirus (CMV) infection in people receiving treatment for ovarian cancer. Researchers collected both saliva and blood samples from 49 participants to compare accuracy. The goal was to see if at-ho…

This study looked at how muscle energy use differs in women with ovarian or endometrial cancer who have lost weight, depending on their body mass index (BMI). Researchers took small muscle samples during surgery to measure how cells make energy. The goal was to understand the bod…