Cancer Survivors' sex drive gets a boost: bupropion shows promise

NCT ID NCT03180294

Completed Symptom relief Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

First seen Apr 28, 2026 · Last updated Apr 28, 2026

Summary

This study tested whether bupropion, a medication that affects brain chemicals, can improve low sexual desire in women who have had breast or gynecologic cancer. About 230 women took either bupropion or a placebo pill for 9 weeks. The main goal was to see if bupropion increased self-reported sexual desire more than the placebo, while also checking for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States
Annie Penn Memorial Hospital

Reidsville, North Carolina, 27320, United States
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Associates In Womens Health

Wichita, Kansas, 67208, United States
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Cape May Court House, New Jersey, 08210, United States
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Egg Harbor, New Jersey, 08234, United States
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Honolulu, Hawaii, 96813, United States
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Honolulu, Hawaii, 96817, United States
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Minneapolis, Minnesota, 55454, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Hematology Oncology Consultants-Clarkston

Clarkston, Michigan, 48346, United States
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Minneapolis, Minnesota, 55415, United States
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Grosse Pointe Woods, Michigan, 48236, United States
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Marietta, Ohio, 45750, United States
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Newark, Delaware, 19713, United States
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Charleston, South Carolina, 29425, United States
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Duluth, Minnesota, 55805, United States
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Maplewood, Minnesota, 55109, United States
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Woodbury, Minnesota, 55125, United States
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St Louis, Missouri, 63131, United States
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Saginaw, Michigan, 48601, United States
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Thornton, Colorado, 80260, United States
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Golden, Colorado, 80401, United States
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Grand Island, Nebraska, 68803, United States
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New Ulm, Minnesota, 56073, United States
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Clarkston, Michigan, 48346, United States
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Pontiac, Michigan, 48341, United States
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Robbinsdale, Minnesota, 55422, United States
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Escanaba, Michigan, 49829, United States
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Mansfield, Ohio, 44903, United States
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Marion, Ohio, 43302, United States
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Honolulu, Hawaii, 96813, United States
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Union, South Carolina, 29379, United States
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Boise, Idaho, 83706, United States
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Sioux City, Iowa, 51101, United States
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Hilton Head Island, South Carolina, 29926-3827, United States
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Springfield, Ohio, 45504, United States
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Denver, Colorado, 80209, United States
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Seaford, Delaware, 19973, United States
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Georgetown, South Carolina, 29440, United States
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University of Hawaii Cancer Center

Honolulu, Hawaii, 96813, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Willis-Knighton Medical and Cancer Center

Shreveport, Louisiana, 71103, United States

Conditions

Explore the condition pages connected to this study.

BREAST CARCINOMA CERVICAL CARCINOMA OVARIAN CARCINOMA POSTMENOPAUSAL UTERINE CORPUS CANCER VAGINAL CARCINOMA VULVAR CARCINOMA