OSTEO ARTHRITIS OF THE KNEE

This study is testing whether a single injection of a new hydrogel (Hydrogel OA 2%) is safe for people with knee osteoarthritis. About 20 adults aged 35 to 75 with knee pain will receive the injection and be monitored for side effects for up to a year. The goal is to see if this …

This study tests whether methotrexate, a drug used for rheumatoid arthritis, can reduce pain and swelling in people with knee osteoarthritis who also have joint inflammation (synovitis). About 70 adults aged 40–70 will receive either methotrexate or standard care for 6 months. Re…

This study tests a new home device that helps people with knee osteoarthritis improve leg control and reduce pain. About 82 adults aged 40-85 with knee pain will use either the leg dexterity trainer or a wobble board for 8 weeks. The goal is to see if the device works better than…

This study looks at whether the BETY exercise program, which combines physical exercises with emotional and social support, can improve pain and quality of life in people with knee osteoarthritis who have already received a joint injection. About 60 adults with moderate knee oste…

This study tests a new, less invasive treatment for people with long-term knee pain from osteoarthritis or after a knee replacement. Doctors use a thin tube to deliver a temporary blocking agent to small arteries in the knee, aiming to reduce inflammation and pain. The study will…

This study tests whether high-intensity pulsed electromagnetic field therapy can reduce pain and improve strength in older adults with knee osteoarthritis. About 64 people aged 60 and older will receive the therapy on their knee or both knee and thigh, plus a home exercise progra…

This study compares two pain relief methods for people having knee replacement surgery due to arthritis. One group gets pain medicine injected into the knee area during surgery. The other group gets that plus extra nerve blocks to numb specific nerves. The goal is to see which ap…

This study compares two different nerve block combinations to see which provides better pain relief after total knee replacement. About 120 adults having knee surgery will be randomly assigned to one of two groups. The goal is to reduce opioid painkiller use and improve early rec…