Magnetic pulses could ease knee arthritis without drugs or surgery
NCT ID NCT07198750
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether high-intensity pulsed electromagnetic field (HI-PEMF) therapy can reduce pain and improve strength in older adults with knee osteoarthritis. 64 participants will receive HI-PEMF on the knee alone or on both the knee and thigh muscle, plus a home exercise program. The goal is to see if this device-based treatment provides lasting pain relief and better mobility.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High-intensity pulsed electromagnetic field (HI-PEMF) therapy device
- What this could lead to
- If it works, this could offer a non-drug, non-surgical option to reduce knee pain and improve mobility in older adults with osteoarthritis.
- What could go wrong
- This is a small, early-stage trial with only 64 participants. The effects may be modest or not last long, and results may not apply to everyone with knee osteoarthritis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 64 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 60 * Clinical and radiological diagnosis of knee OA grade I-IV * Pain ≥ 3 on Numeric Analog Scale for \>6 months * Can walk (with/without aid) * Cognitive ability to follow instructions * Signed informed consent * Availability for 9 treatment sessions and home exercise Exclusion Criteria * Prior total knee arthroplasty (unilateral or bilateral) * Neurological disorders affecting motor function or cognition (e.g., Parkinson's disease, stroke, moderate to severe dementia) * Active inflammatory rheumatic diseases (e.g., rheumatoid arthritis, lupus) * Presence of pacemakers, implantable defibrillators, or metallic implants near the treatment area * Current use of other physical therapy modalities for pain (e.g., electrotherapy, ultrasound, TENS) outside the study protocol * Participation in another clinical trial within the past 3 months * Current use of NSAIDs or systemic/local corticosteroids (including intra-articular injections) * Open wounds or active infections at the treatment site * Decompensated cardiac conditions or medical contraindication to exercise * Vestibular disorders that affect balance and interfere with functional assessments * Uncorrected visual impairment interfering with gait or balance (visual acuity worse than 20/60 in the better eye, assessed by Snellen chart) Withdrawal Criteria: * Participants who complete fewer than 7 out of the 9 planned intervention sessions (i.e., less than 80% adherence) * Occurrence of serious adverse events related to the intervention that contraindicate continuation * Repeated non-compliance with the home exercise program, documented in at least two consecutive weekly follow-up reports * Voluntary withdrawal of consent at any time during the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Civil de Guadalajara "Fray Antonio Alcalde"
RECRUITINGGuadalajara, Jalisco, 44280, Mexico
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