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Magnetic pulses could ease knee arthritis without drugs or surgery

NCT ID NCT07198750

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether high-intensity pulsed electromagnetic field (HI-PEMF) therapy can reduce pain and improve strength in older adults with knee osteoarthritis. 64 participants will receive HI-PEMF on the knee alone or on both the knee and thigh muscle, plus a home exercise program. The goal is to see if this device-based treatment provides lasting pain relief and better mobility.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-intensity pulsed electromagnetic field (HI-PEMF) therapy device
What this could lead to
If it works, this could offer a non-drug, non-surgical option to reduce knee pain and improve mobility in older adults with osteoarthritis.
What could go wrong
This is a small, early-stage trial with only 64 participants. The effects may be modest or not last long, and results may not apply to everyone with knee osteoarthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 60 * Clinical and radiological diagnosis of knee OA grade I-IV * Pain ≥ 3 on Numeric Analog Scale for \>6 months * Can walk (with/without aid) * Cognitive ability to follow instructions * Signed informed consent * Availability for 9 treatment sessions and home exercise Exclusion Criteria * Prior total knee arthroplasty (unilateral or bilateral) * Neurological disorders affecting motor function or cognition (e.g., Parkinson's disease, stroke, moderate to severe dementia) * Active inflammatory rheumatic diseases (e.g., rheumatoid arthritis, lupus) * Presence of pacemakers, implantable defibrillators, or metallic implants near the treatment area * Current use of other physical therapy modalities for pain (e.g., electrotherapy, ultrasound, TENS) outside the study protocol * Participation in another clinical trial within the past 3 months * Current use of NSAIDs or systemic/local corticosteroids (including intra-articular injections) * Open wounds or active infections at the treatment site * Decompensated cardiac conditions or medical contraindication to exercise * Vestibular disorders that affect balance and interfere with functional assessments * Uncorrected visual impairment interfering with gait or balance (visual acuity worse than 20/60 in the better eye, assessed by Snellen chart) Withdrawal Criteria: * Participants who complete fewer than 7 out of the 9 planned intervention sessions (i.e., less than 80% adherence) * Occurrence of serious adverse events related to the intervention that contraindicate continuation * Repeated non-compliance with the home exercise program, documented in at least two consecutive weekly follow-up reports * Voluntary withdrawal of consent at any time during the study

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Civil de Guadalajara "Fray Antonio Alcalde"

    RECRUITING

    Guadalajara, Jalisco, 44280, Mexico

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