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New procedure aims to ease knee arthritis pain by blocking blood flow

NCT ID NCT07361198

Symptom relief Sponsor: Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a minimally invasive treatment for chronic knee pain from osteoarthritis or after knee replacement. Doctors guide a thin tube to knee arteries and inject a temporary agent to reduce blood flow to inflamed tissue. The goal is to see if this procedure safely reduces pain and improves knee function over 24 months. The study enrolls 20 adults aged 40-80 who haven't gotten enough relief from standard treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 40 to 80 years * Clinical symptoms consistent with chronic knee pain * Radiographically confirmed knee osteoarthritis of Kellgren-Lawrence grade II-IV or persistent knee pain following total knee arthroplasty * Insufficient pain relief after standard conservative treatment (e.g., pharmacological therapy, physical therapy, or injections) * Ability to understand the study procedures and provide written informed consent \_ Willingness and ability to comply with the study procedures and follow-up schedule Exclusion Criteria: * Active local or systemic infection * Known coagulation disorders or ongoing anticoagulation that cannot be safely interrupted * Significant peripheral arterial disease affecting the lower limbs * Known allergy or contraindication to iodinated contrast agents * Severe renal impairment * History of fibromyalgia or other generalized chronic pain syndromes that may confound pain assessment * Pregnancy or breastfeeding

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteo arthritis of the knee Osteoarthitis Osteoarthritic knee pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Masarykova nemocnice v Ústí nad Labem

    RECRUITING

    Ústí nad Labem, 40011, Czechia

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