NEUROPATHIC PAIN

This study planned to test whether photobiomodulation (a type of light therapy) could reduce nerve pain and improve sensation in one woman after mastectomy. The participant would have received 6 weeks of treatment while researchers measured pain, touch, strength, and quality of l…

This study tests a spinal cord stimulator (BurstDR) for people with painful diabetic neuropathy. Twenty adults with long-term nerve pain in their legs will try a temporary device for one week. If their pain drops by at least half, they get a permanent implant. Researchers will tr…

This study tests whether a noninvasive electrical stimulation device placed on the back can reduce nerve-related pain. About 62 adults with chronic nerve pain will receive either real or fake (sham) stimulation during their hospital stay. Researchers will track pain levels, sleep…

This study looks at whether adding a muscle stimulation program to existing BurstDR therapy can further reduce chronic back pain and improve quality of life. About 60 adults with persistent back pain who already have a spinal cord stimulator implanted will use the extra muscle st…

This study tests a new drug (LY3848575) to see if it safely reduces chronic nerve pain that starts in the feet and moves up the legs. About 558 adults with this type of pain for at least 6 months will receive either the drug or a placebo for up to 30 weeks. The main goal is to me…

This study looks at how well a closed-loop spinal cord stimulator works for people with long-term pain. Researchers will track pain levels and quality of life in 25 adults who have had pain for at least 6 months. The device automatically adjusts stimulation to help reduce pain.

This study looks at whether taking vitamin D supplements can lessen nerve pain caused by taxane chemotherapy. About 120 people with low vitamin D levels who are starting chemo will be randomly assigned to get vitamin D or standard care. The goal is to see if vitamin D helps reduc…

This study aims to find out how common nerve problems are in people who feel discomfort in their eyes. Researchers will test 1,000 participants with eye discomfort to see if they have a condition called neuropathic corneal pain, and how it overlaps with dry eye disease. The goal …

This study looks at how the brain and nervous system react differently in people with various types of long-term pain, such as nerve pain or pain from tissue damage. Researchers will use questionnaires, thinking tests, and brain wave measurements to track changes over a year. The…

This study was designed to observe brain wave patterns in adults with chronic nerve pain who were scheduled to receive ketamine infusions. Researchers wanted to see if changes in brain activity could predict how well ketamine works for pain and mood. However, the study was withdr…

This study looks at how common nerve-related pain is in people with knee osteoarthritis and whether it's linked to night pain. Researchers will ask 150 participants about their pain and sleep quality. The goal is to better understand these connections, not to test a new treatment…