NEUROPATHIC PAIN

This study is testing a small, implanted device that sends mild electrical pulses to the spinal cord to reduce chronic nerve pain in the feet and legs caused by diabetes. Up to 20 adults with painful diabetic neuropathy who haven't gotten enough relief from standard pain medicati…

This study aimed to see if a special light therapy could help reduce nerve pain and improve skin sensation for one woman after a mastectomy. The participant would have used a light device at home for six weeks while tracking her pain and sensation. Researchers planned to compare …

This study is testing whether a noninvasive electrical stimulation device placed on the back can help reduce nerve pain and improve daily life for people with chronic low back pain. About 62 participants will be randomly assigned to receive either real stimulation or a sham (plac…

This study is testing whether a specific relaxation technique can help people with type 2 diabetes feel better. Researchers are working with 88 participants to see if guided muscle relaxation and breathing exercises, done daily for six weeks, can reduce nerve pain and fatigue whi…

This study is observing how well a new type of spinal cord stimulator works for people with long-term, hard-to-treat pain. The device, called evoke®, is already approved and being used in real-world patients. Researchers are tracking 25 adults with severe chronic pain to see how …

This study is testing an experimental drug called LY3848575 to see if it is safe and effective at reducing chronic nerve pain that starts in the feet and moves up the legs. It will compare the drug to a placebo in about 450 adults who have had this type of pain for at least six m…

This study is comparing two ways to manage severe pain from cancer. One group gets a small pump implanted near the spine to deliver pain medicine directly. The other group continues with standard pain pills. Researchers will track which method better controls pain, reduces medica…

This study aims to understand how often people with knee osteoarthritis experience nerve-related pain and how it connects to pain that wakes them up at night. Researchers will follow 150 participants with moderate to severe knee arthritis to measure their pain levels, sleep quali…

This study aims to measure how common nerve-related pain is in people who experience chronic eye discomfort, often diagnosed as dry eye. Researchers will test 1,000 participants with eye drops to see if their pain is linked to nerve problems. The goal is to better understand the …

This study aims to understand how three different types of chronic pain affect the brain's pain processing system. Researchers will follow 185 patients for one year, using questionnaires and brain tests to measure changes. The goal is to gather knowledge that could lead to more p…