NEUROBLASTOMA
Clinical trials for NEUROBLASTOMA explained in plain language.
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Engineered immune cells plus chickenpox vaccine take on childhood cancers
Disease control OngoingThis early-phase study tests a new treatment for advanced osteosarcoma and neuroblastoma that has not responded to standard therapy. It combines specially engineered immune cells (GD2-CAR T cells) with a chickenpox vaccine to help the cells last longer in the body. The main goals…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 01, 2026 15:28 UTC
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Immune cells join fight against childhood cancer
Disease control OngoingThis early-stage trial tests a new approach for children with neuroblastoma that has come back or not responded to treatment. It combines the patient's own expanded natural killer (NK) cells with standard antibody therapy (dinutuximab), and possibly a drug called lenalidomide. Th…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated May 01, 2026 15:27 UTC
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Smart therapy for neuroblastoma: less toxicity, same control?
Disease control OngoingThis study tests whether doctors can safely tailor treatment for children with non-high-risk neuroblastoma based on the tumor's biology and how it responds over time. Some children may only need monitoring instead of immediate treatment, potentially avoiding harsh side effects. T…
Matched conditions: NEUROBLASTOMA
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated May 01, 2026 15:27 UTC
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New hope for kids with tough cancers: experimental drug CLR 131 enters human testing
Disease control OngoingThis early-stage study tests an experimental drug, CLR 131, in 30 children, adolescents, and young adults whose solid tumors, lymphoma, or brain tumors have returned or not responded to standard treatments. The main goal is to find a safe dose and check for side effects. Research…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Cellectar Biosciences, Inc. • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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Engineered immune cells target tough childhood cancer
Disease control OngoingThis early-phase study tests a new type of gene therapy for children with neuroblastoma that has come back or not responded to treatment. The therapy uses the patient's own immune cells (T cells) that are modified in the lab to recognize and attack neuroblastoma cells. The study …
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Experimental antibody cocktail targets tough childhood cancer
Disease control OngoingThis study tests a combination of two drugs—an antibody called Hu3F8 and GM-CSF—in children with high-risk neuroblastoma that has come back or not responded to standard therapy. The main goal is to find a safe dose and check for side effects. About 186 participants will be enroll…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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New hope for kids with tough cancer: drug combo trial launches
Disease control OngoingThis early-phase study tests a three-drug combination (sorafenib, cyclophosphamide, and topotecan) in children and young adults with neuroblastoma that has come back or not responded to treatment. The main goal is to find the safest dose of sorafenib when given with the other two…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
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New scan could spot hidden tumors in kids
Diagnosis OngoingThis early-phase study tests a radioactive tracer called 18F-DA to see if it can create clearer PET scan images of neuroblastoma and pheochromocytoma tumors in children. The standard tracer often misses very small areas of disease. About 20 participants will receive the tracer an…
Matched conditions: NEUROBLASTOMA
Phase: EARLY_PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Diagnosis
Last updated May 01, 2026 15:28 UTC
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Could a 4-Hour infusion replace 20-Hour hospital stays for kids with neuroblastoma?
Symptom relief OngoingThis study tests whether giving the drug dinutuximab over 4 hours or less is safe and doable for children with high-risk neuroblastoma. Currently, the standard infusion takes 10-20 hours and requires a hospital stay. The goal is to see if a faster infusion can be given in an outp…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Children's Hospital Los Angeles • Aim: Symptom relief
Last updated Apr 29, 2026 15:03 UTC
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Hidden gene glitches: could new mutations spark cancer in kids?
Knowledge-focused OngoingThis study searches for brand-new gene changes that appear in children but not in their parents, which might raise cancer risk. Researchers will compare DNA from 1,275 cancer patients (with breast, colon, or other cancers) and their healthy parents. The goal is to find these hidd…
Matched conditions: NEUROBLASTOMA
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC