Hidden gene changes could reveal who gets cancer
NCT ID NCT00996710
First seen Nov 05, 2025 · Last updated Jun 22, 2026 · Updated 31 times
Summary
This study searches for new gene changes (mutations) that appear in cancer patients but not in their healthy parents. By comparing DNA from 1,275 people with certain cancers and their families, researchers hope to find genetic clues that increase cancer risk. The goal is to better understand how these new mutations contribute to cancer and potentially identify people at higher risk.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify people at higher risk for certain cancers by detecting new gene changes that are not inherited.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to immediate clinical changes, and findings may not apply to all cancer types or populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.