NEUROBLASTOMA
Clinical trials for NEUROBLASTOMA explained in plain language.
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Radioactive cocktail shows promise for tough childhood cancer
Disease control CompletedThis early-phase study tested a combination of a radioactive drug (131I-MIBG) and two chemotherapy drugs (irinotecan and vincristine) in 26 children with high-risk neuroblastoma that had come back or not responded to standard treatment. The goal was to find the safest dose of the…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated May 01, 2026 15:26 UTC
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New immunotherapy combo shows promise in keeping high-risk childhood cancer at bay
Disease control CompletedThis study tested a combination of Hu3F8 (an antibody) and GM-CSF (an immune booster) along with isotretinoin in 59 children with high-risk neuroblastoma who had achieved their first remission. The goal was to see if this immunotherapy could prevent the cancer from growing back. …
Matched conditions: NEUROBLASTOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New hope for kids with tough cancer: experimental drug tested
Disease control CompletedThis early-stage study tested an intravenous form of the drug fenretinide in 17 children whose neuroblastoma had come back or was resistant to treatment. The main goals were to find the safest dose and understand side effects. The drug works by stopping tumor cells from growing o…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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Smaller radiation dose may cut side effects for kids with neuroblastoma
Disease control CompletedThis study tested whether a smaller dose of radiation can control high-risk neuroblastoma while reducing long-term side effects. 78 children with high-risk neuroblastoma received reduced-dose radiation to the tumor site. Researchers tracked tumor response and side effects over ti…
Matched conditions: NEUROBLASTOMA
Phase: EARLY_PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Double-Dose radiation attack shows promise for tough childhood cancer
Disease control CompletedThis early-phase study tested a new approach for children with neuroblastoma that did not respond to standard treatments. It used two doses of a radioactive drug (I-MIBG) to target cancer cells, followed by a stem cell transplant to restore healthy blood cells. The goal was to fi…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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New hope for neuroblastoma: targeted pill shows promise in early trial
Disease control CompletedThis early-phase study tested a daily pill called lorlatinib in 65 people with ALK-driven neuroblastoma, a rare nerve cancer that had come back or not responded to standard treatments. The goal was to find the safest dose and check for side effects, both when given alone and with…
Matched conditions: NEUROBLASTOMA
Phase: PHASE1 • Sponsor: New Approaches to Neuroblastoma Therapy Consortium • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC