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Engineered immune cells target tough childhood cancer

NCT ID NCT01822652

First seen Apr 06, 2026 · Last updated Apr 29, 2026 · Updated 4 times

Summary

This early-phase study tests a new type of gene therapy for children with neuroblastoma that has come back or not responded to treatment. The therapy uses the patient's own immune cells (T cells) that are modified in the lab to recognize and attack neuroblastoma cells. The study aims to find the safest dose and includes chemotherapy and an additional drug (pembrolizumab) to help the modified cells work better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.