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Gene-Edited immune cells take on childhood cancer

NCT ID NCT01822652

First seen Apr 06, 2026 · Last updated May 30, 2026 · Updated 7 times

Summary

This early-phase study tests a new gene therapy for children whose neuroblastoma has returned or not responded to treatment. Researchers take the patient's own immune cells, add genes to help them recognize and attack the cancer, and give them back along with chemotherapy and an immunotherapy drug. The main goal is to find the safest dose and see how long the modified cells last in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

neuroblastoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.