NEOPLASMS

This phase 2 trial tests a new vaccine (TriAdeno) plus an immune-boosting drug (N-803) in 52 men with early-stage prostate cancer who are currently on active surveillance. The goal is to see if the combination can increase immune cell activity inside the tumor and possibly slow o…

This study tests an experimental drug called LRK-4189, given alone or with standard chemotherapy, for adults with advanced solid tumors that have not responded to prior treatment. The main goal is to check the drug's safety and find the best dose. About 120 participants will take…

This early-phase study tests a drug called zanidatamab in 10 adults with advanced HER2-positive solid tumors (like endometrial, bladder, or pancreatic cancer) that have worsened after at least one prior treatment. Participants receive the drug by IV every two weeks. The main goal…

This study looks at whether adding a mix of nutritional supplements (spirulina, bifidobacterium, fish oil, grape seed, blueberry, and ganoderma spore oil) to standard steroid treatment can help people with severe lung inflammation caused by cancer immunotherapy. About 60 adults w…

This study is testing a new imaging agent called 68Ga-SFB6-ZN01 that attaches to a protein found on many cancer cells. About 98 adults with confirmed or suspected cancer will get one injection and one PET/CT scan. The goal is to see if the agent is safe and can accurately detect …

This pilot study tests an online program called Finding My Way-UK for people who finished curative cancer treatment in the past year. The program includes six self-guided modules on coping, emotions, and body image. Researchers will check if it's easy to use and if it helps with …

This study follows 100 young cancer patients (ages 0-18) who freeze their ovarian tissue before treatment. Researchers want to see how safe the procedure is and how many go on to have a baby after transplanting the tissue back. The goal is to learn if this method effectively pres…

This study tests a non-invasive imaging technique called LC-OCT for diagnosing basal cell carcinoma, the most common skin cancer. Researchers will review medical records of about 300 patients to see if LC-OCT can accurately detect cancer and guide treatment without needing a biop…

This study looks at where 300 cancer patients treated at Delafontaine Hospital live and how long it takes them to get there. By mapping home addresses and travel methods, researchers hope to uncover social and transportation barriers to care. The goal is to improve support and re…