MYELOMA

This early-stage trial tests a new daily pill, KTX-1001, for people with multiple myeloma that has returned or stopped responding to other treatments. The study aims to find a safe dose and see if the drug can shrink tumors or slow the cancer. About 125 adults who have tried at l…

This study compares different infection prevention strategies in 900 people with blood cancers like myeloma, lymphoma, and leukemia. The goal is to find which approach is safest and most effective at preventing serious infections. Participants will receive one of several treatmen…

This study tests whether a combination of elotuzumab, iberdomide, and dexamethasone can help control multiple myeloma that has returned or not responded to treatment, after patients have already received a CAR-T cell therapy called idecabtagene vicleucel. About 49 adults with rel…

This study tests whether the drug elranatamab, given after CAR-T cell therapy (cilta-cel), can help people with high-risk relapsed myeloma live longer without their cancer getting worse. About 39 participants who have already received CAR-T therapy will take elranatamab as a main…

This study tests a new treatment using cord blood-derived NK cells that are genetically engineered to recognize and attack multiple myeloma cells. The goal is to find a safe dose and see if it can control the disease in patients whose cancer has returned or not responded to prior…

This early-stage trial tests a drug called belantamab mafodotin in 30 people with high-risk smoldering multiple myeloma, a condition that often leads to active cancer. The main goal is to find the safest dose and see if the drug can control the disease. Participants receive the d…

This study looks at different ways to prevent serious infections in people with blood cancers like myeloma, lymphoma, and leukemia. About 900 participants will receive either antibiotics or immunoglobulin therapy to see which approach works better at keeping them infection-free. …

This study looks at different ways to prevent infections in people with blood cancers like myeloma, leukemia, and lymphoma. It compares treatments such as antibiotics and immunoglobulin therapy to see which works best. About 900 participants will be enrolled, and the goal is to r…

This study compares two common treatments—immunoglobulin and antibiotics—to see which is better at preventing serious infections in people with blood cancers like myeloma, lymphoma, or leukemia. About 900 adults will take part. The goal is to find the safest and most effective wa…

This study looks at whether people with multiple myeloma can safely give themselves a standard chemotherapy injection (bortezomib) at home, instead of always going to the hospital. About 100 adults who are stable on treatment and have already had several injections in the clinic …

This study tests a home-based exercise and nutrition program for 40 adults with lymphoma or myeloma who are about to receive CAR-T cell therapy. Participants follow a personalized plan using a tablet and get support from a rehab team online. The goal is to see if this approach im…

This study tests a program that gives blood cancer patients access to blood transfusions at home while in hospice care. The goal is to see if this improves quality of life, mood, and reduces hospital visits near the end of life. About 700 adults with advanced blood cancers like l…

This study is testing whether a special PET scan called 18F FLT can detect signs of leukemia or related blood cancers after treatment. About 60 people aged 4 to 80 with relapsed or hard-to-treat leukemia or myeloma will get the scan before and after therapy. The goal is to see if…

This study aims to collect blood samples (liquid biopsies) from 2,500 people with cancer or at high risk for cancer. The samples will be stored and used in future research to better understand how cancers grow and respond to treatment. No new treatments are being tested; the goal…

This study looks at how services from Blood Cancer United (formerly The Leukemia & Lymphoma Society) affect people with blood cancers like leukemia, lymphoma, and myeloma. Researchers will track 400 patients over time to see if the organization helps with access to care, quality …