MYELOMA

This early-phase study tested whether removing a specific type of immune cell (regulatory T cells) before a stem cell transplant is safe and possible for people with multiple myeloma. Thirty participants received either standard transplant or transplant with T cell removal. The g…

This study tested a drug called elranatamab in 39 Chinese patients with multiple myeloma that stopped responding to standard treatments. The drug works by helping the body's immune system attack the cancer cells. The goal was to see if it is safe and can shrink or control the can…

This early-phase study tested a new drug (BMS-986345) combined with an existing drug (duvelisib) in 14 people with blood cancers like lymphoma, myeloma, and leukemia. The main goal was to find a safe dose and check for side effects. Results help guide future research, but this is…

This study looked at a combination of three drugs (bortezomib, lenalidomide, and dexamethasone, known as VRD) for people newly diagnosed with multiple myeloma, a type of blood cancer. Over 400 patients took part, and some also had a stem cell transplant. After initial treatment, …

This study tested whether taking lenalidomide (Revlimid) after a stem cell transplant helps keep myeloma in check longer. Over 600 patients under 65 who had no signs of progression after transplant were randomly assigned to receive either lenalidomide or a placebo. The goal was t…

This early-phase study tested a new treatment called FT576, given alone or with another drug (daratumumab), in 31 people whose multiple myeloma had returned or stopped responding to prior therapies. The goal was to find the safest dose and see if the combination can help control …

This study tested whether a second stem cell transplant from a matched donor could help younger myeloma patients (under 65) who had a good response to their first transplant. Thirteen patients received a reduced-intensity conditioning regimen followed by donor stem cells. The goa…

This study looked at 700 adults up to age 65 with multiple myeloma to see if high-dose therapy with a stem cell transplant works better than standard drug treatment. The goal was to find out which approach keeps the cancer from growing longer. Results help doctors decide the best…

This study tested a new way to help people with blood cancers like leukemia and lymphoma get hospice care earlier. Normally, patients delay hospice because they need blood transfusions for symptom relief, but hospices can't afford to provide them. The study paid for transfusions …

This early study looked at whether repeated hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) is safe for people with multiple myeloma who are about to receive high-dose chemotherapy and a stem cell transplant. 29 adults with myeloma took part. The main g…

This study looked at how well the Pfizer COVID-19 vaccine triggered an immune response in 196 adults with weakened immune systems (like kidney transplant patients or those with cancer) compared to healthy adults. Researchers measured antibody levels in the blood and nose to see i…

This study looked at whether a simple blood test and a whole-body MRI scan can accurately detect leftover cancer cells (minimal residual disease) in people with multiple myeloma. The goal is to see if these non-invasive methods could replace the standard bone marrow biopsy, which…

This study looked at whether a home-based exercise program is practical for people aged 65 and older with lymphoma, leukemia, or myeloma who are about to receive CAR-T cell therapy. Twenty participants were asked to do supervised resistance training and moderate aerobic exercise.…