MORTALITY

This study tested whether changing the national vaccine policy in Guinea-Bissau to give measles shots to all children up to 3 years old (instead of stopping at 12 months) could lower death rates. About 3,500 children aged 9-35 months who had not yet received the measles vaccine t…

This study tested whether adding the drug bezlotoxumab to standard treatment could prevent serious outcomes like organ failure, infection return, or death in people with a severe C. diff infection. The trial included 44 adults who were identified as high-risk using a special scor…

This study tested whether a physical activity program delivered by mail and phone could help older women prevent serious health problems like heart attacks, strokes, hip fractures, and falls. About 50,000 women already in the Women's Health Initiative took part. The program provi…

This study tested whether giving the oral polio vaccine (OPV) to adults over 50 could lower their risk of getting sick or dying from COVID-19 and other infections. Researchers in Guinea-Bissau gave OPV to some people and no vaccine to others, then tracked health for 6 months. The…

This study looked at older adults (65+) having surgery to see if postoperative delirium (sudden confusion after surgery) makes frailty worse and raises the risk of death within a year. Researchers followed over 6,000 patients, measuring frailty before and one month after surgery,…

This study looked at nearly 30,000 older adults (65+) having non-cardiac surgery to see if levels of homocysteine, a substance in the blood, are linked to complications like kidney injury or death. Researchers measured homocysteine before and after surgery. The goal was to find o…

This study looked at whether a simple frailty score (Rockwood Frailty Index) can predict how long older adults might live after being treated at home instead of in a hospital. Researchers followed 2,610 patients aged 65 and older who were in a Hospital-at-Home program. They found…

This study looked at whether giving extra oxygen during heart-lung bypass affects kidney function after heart surgery. 104 adults having planned heart surgery took part. The goal was to see if extra oxygen helps or harms the kidneys and other organs.

This study looked at 1,250 adults with advanced cancer who visited the emergency room. Researchers checked medical records to find factors linked to survival in the next 90 days. The goal is to help doctors identify patients who need extra support or palliative care sooner.

This study looked at 2,744 older adults (65+) who came to the emergency room for non-injury reasons. Researchers checked how well different early warning scores—like NEWS and qSOFA—could predict who would die within 28 days. The goal was to find which score works best for this ag…

This study looked at 600 adults with severe COVID-19 lung failure who were treated with high-flow nasal oxygen and placed on their stomachs while awake. The goal was to see if this combination could reduce the need for a breathing tube and lower death rates. Researchers also want…

This study looked at 1,000 adults who had a severe type of heart attack (STEMI). Researchers checked their nutritional status using two simple blood test scores (CONUT and PNI) at the time they were admitted to the hospital. The goal was to see if those with poorer nutrition had …

This study reviewed medical records of 901 infants who had surgery for aortic coarctation (a narrowed heart artery) before age one. Researchers wanted to find out how many later developed high blood pressure or re-narrowing of the artery. The goal is to better understand these lo…

This study looked at 50,000 living kidney donors in Canada to see if they have a higher risk of heart problems or death later in life compared to similar people who didn't donate. Researchers used health records from 1992 to 2024 to track heart attacks, strokes, and deaths. The g…

This study looked at whether common blood tests can help predict the risk of death in people with suspected sepsis in the intensive care unit (ICU). Researchers reviewed records from 250 adults to see if levels of certain markers like PCT, CRP, and lactate were linked to survival…

This study looked at 260 adults in the intensive care unit (ICU) who needed oxygen therapy. Researchers found that about 60% of patients had too much oxygen in their blood (hyperoxemia). Those with high oxygen levels had longer stays in the ICU and hospital, and a much higher cha…

This study tested whether using a video to measure capillary refill time (how fast skin color returns after pressing it) is more reliable than the usual visual method. Researchers compared both methods in 59 intensive care unit patients. The goal was to see if the video method gi…