MORBID OBESITY
Clinical trials for MORBID OBESITY explained in plain language.
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Smartphone app aims to boost Pre-Surgery weight loss
Disease control CompletedThis study tested if a mobile app (Care4Today®) helps people with severe obesity lose weight before gastric bypass surgery. 142 adults used either the app or standard care. The goal was to see if the app leads to more weight loss and better patient knowledge and satisfaction befo…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospital Universitari de Bellvitge • Aim: Disease control
Last updated May 26, 2026 10:30 UTC
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New weight loss surgery shows promise in study
Disease control CompletedThis study tested a newer, simpler weight loss surgery called SADI-S against a standard, more complex surgery (BPD-DS) in 62 adults with severe obesity. The goal was to see if SADI-S is safer and just as effective for weight loss and related health problems like diabetes. Researc…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 26, 2026 10:23 UTC
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Weight-Loss surgery may help you walk better
Disease control CompletedThis study tested whether sleeve gastrectomy, a weight-loss surgery, improves how well people with severe obesity can walk. Researchers measured walking distance and quality of life before surgery and 6 months after in 99 adults. The goal was to see if the surgery leads to better…
Matched conditions: MORBID OBESITY
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated May 26, 2026 10:23 UTC
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Lidocaine may cut opioid use after bariatric surgery
Symptom relief CompletedThis study tested whether giving the numbing drug lidocaine through a vein during weight-loss surgery could help people recover faster. 180 adults having bariatric surgery took part. The goal was to see if lidocaine could lower the need for strong painkillers (opioids) after the …
Matched conditions: MORBID OBESITY
Phase: PHASE3 • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated May 26, 2026 10:25 UTC
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New nerve block eases pain after sleeve gastrectomy
Symptom relief CompletedThis study looked at whether a specific nerve block (external oblique intercostal block) can reduce pain after laparoscopic sleeve gastrectomy, a weight-loss surgery. Twenty patients aged 18-65 participated. Researchers measured how much pain relief the block provided and how muc…
Matched conditions: MORBID OBESITY
Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Opioid-Free anesthesia shows promise for bariatric surgery patients
Symptom relief CompletedThis study tested whether avoiding opioids during weight-loss surgery could reduce pain and side effects afterward. Sixty adults with severe obesity were randomly assigned to receive either opioid-free or standard opioid anesthesia. Researchers measured pain levels, need for extr…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospital dos Lusíadas • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Mist before knife: new approach may steady vital signs during obesity surgery
Symptom relief CompletedThis study tested whether breathing in a medication called dexmedetomidine before surgery can prevent dangerous spikes in heart rate and blood pressure during weight-loss surgery in people with obesity. 90 adults with a BMI between 30 and 45 took part. The goal was to see if this…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated May 20, 2026 11:53 UTC
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Wearing activity monitors reveals hidden links to Well-Being in severe obesity
Knowledge-focused CompletedThis study looked at how physical activity relates to quality of life and mental health in 38 adults with severe obesity (BMI over 40). Participants wore activity monitors for 6 weeks to track sitting, standing, and movement. The goal was to understand these connections, not to t…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 10:34 UTC
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Stomach pouch size may predict weight regain after bariatric surgery
Knowledge-focused CompletedThis study looked at 46 people with severe obesity who had gastric bypass or sleeve gastrectomy. Researchers used a special CT scan to measure stomach pouch volume at 3 and 12 months after surgery. The goal was to see if a larger pouch is linked to weight regain, which could help…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated May 26, 2026 10:32 UTC
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When you eat may reshape your gut bugs, study suggests
Knowledge-focused CompletedThis study looked at how the number of meals per day and the timing of calories affect gut bacteria in 34 adults—23 with morbid obesity and 11 without. Researchers analyzed diet records and stool samples to compare gut microbial profiles. The goal was to understand links between …
Matched conditions: MORBID OBESITY
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated May 26, 2026 10:29 UTC
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New study seeks safer intubation for obese patients
Knowledge-focused CompletedThis study looked at 725 severely obese adults (BMI 35 or higher) to find the safest way to insert a breathing tube before surgery. Researchers compared giving oxygen through a face mask during the procedure versus not using a mask. The goal was to see which method causes fewer c…
Matched conditions: MORBID OBESITY
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Weight-Loss surgery may change how blood thinners work
Knowledge-focused CompletedThis study looked at how the blood thinner rivaroxaban behaves in people with severe obesity and in those who had weight-loss surgery (gastric bypass or sleeve gastrectomy). Sixty-seven participants took rivaroxaban for 8 days, and researchers measured drug levels and blood clott…
Matched conditions: MORBID OBESITY
Phase: PHASE1 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated May 18, 2026 12:01 UTC