MITRAL REGURGITATION

This study will track 1000 people with mitral regurgitation, a condition where a heart valve doesn't close tightly, causing blood to leak backward. Participants will receive a tiny clip (MitraClip G5) to repair the valve through a tube inserted in a vein, avoiding open-heart surg…

This study looks at whether making a small opening between the upper chambers of the heart during mitral valve surgery can help prevent heart failure symptoms after the operation. The trial will include 50 adults with severe mitral regurgitation (a leaky heart valve) who are sche…

This early study tests a device called the MRace implant to treat moderate-to-severe mitral regurgitation, a condition where the heart's mitral valve leaks. About 15 people will get the implant and be followed for up to 5 years to see if it safely reduces the leak and improves sy…

This study tests whether repairing both the mitral and tricuspid heart valves at the same time is better than fixing only the mitral valve in people with severe leakage in both valves. About 404 adults with moderate-to-severe or severe leakage will be randomly assigned to one of …

This study is a registry that will follow 150 people with severe mitral regurgitation who receive the HighLife mitral valve replacement system. The goal is to see how well the device works and how safe it is in everyday medical practice. Participants will be monitored for technic…

This study tests a new heart valve (SAPIEN X4) for people with mitral valve disease who are too high-risk for surgery. About 125 participants will receive the valve through a catheter. The goal is to see if the valve is safe and improves heart function and quality of life.

This study looks at whether a special heart ultrasound technique, called speckle tracking, can better predict survival and complications after mitral valve surgery compared to the current standard method. Researchers will follow 300 adults with severe mitral regurgitation who are…

This study will use a small heart monitor (implantable loop recorder) for up to three years to find hidden atrial fibrillation in 100 people with moderate-to-severe mitral valve regurgitation who have few or no symptoms. The goal is to learn how common these hidden heart rhythm p…