MITRAL REGURGITATION
Clinical trials for MITRAL REGURGITATION explained in plain language.
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New heart valve implant offers hope for patients with leaky mitral valve
Disease control OngoingThis study tested a new device called the Tendyne mitral valve, which is implanted without open-heart surgery to treat a leaky mitral valve (mitral regurgitation). About 103 people with moderate-to-severe symptoms took part, and some were compared to those receiving an existing d…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 26, 2026 07:57 UTC
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New heart valve procedure for High-Risk patients halted before it began
Disease control TerminatedThis study aimed to test a new device called the Cardiovalve, which is placed through a leg vein to replace a leaky mitral heart valve without open-heart surgery. It was designed for people with severe mitral regurgitation who were considered too high-risk for traditional surgery…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated May 26, 2026 07:50 UTC
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Heart valve surgery gets a smarter Decision-Making tool
Disease control OngoingThis study looks at a common heart problem where the mitral valve leaks because of heart disease. Currently, surgeons choose to repair or replace the valve based on their own experience. This trial tests a new approach: using a set of specific measurements (an algorithm) to decid…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated May 26, 2026 07:26 UTC
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New heart valve fix through a leg vein avoids Open-Heart surgery
Disease control OngoingThis study tests a new device called the Cardiovalve, which is threaded through a vein in the leg to fix a leaky mitral valve without open-heart surgery. It includes 30 people with severe mitral regurgitation who are too high-risk for traditional surgery. The goal is to see if th…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated May 26, 2026 07:25 UTC
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New heart valve without open surgery: hope for High-Risk patients
Disease control ENROLLING_BY_INVITATIONThis study tests a new replacement heart valve for people with severe mitral regurgitation (a leaky heart valve) who are too high-risk for open-heart surgery. The valve is delivered through a tube inserted in a leg vein, avoiding a large chest incision. The study will enroll 10 p…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New heart valve repair device goes head-to-head with standard treatment
Disease control OngoingThis study tests a new device called PASCAL against an existing device, MitraClip, for repairing leaky mitral valves in the heart. About 1,200 people with mitral regurgitation who are too high-risk for open-heart surgery took part. The goal is to see if PASCAL is as safe and effe…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New clip procedure could offer High-Risk heart patients a safer alternative to surgery
Disease control OngoingThis study tests whether a minimally invasive clip repair (MitraClip) is as effective as open-heart surgery for people with severe mitral regurgitation who are at high risk for surgery. About 330 participants will be randomly assigned to one of the two treatments and followed for…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Nantes University Hospital • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Heart MRI may outshine ultrasound for valve surgery timing
Knowledge-focused OngoingThis study looks at whether using a cardiac MRI (CMR) instead of the usual ultrasound helps doctors make better decisions about heart valve surgery for people with severe mitral regurgitation (a leaky heart valve). About 260 adults with no symptoms but a severe leak will be follo…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Centro Cardiologico Monzino • Aim: Knowledge-focused
Last updated May 26, 2026 07:23 UTC