METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Clinical trials for METASTATIC MALIGNANT NEOPLASM IN THE BRAIN explained in plain language.
Never miss a new study
Get alerted when new METASTATIC MALIGNANT NEOPLASM IN THE BRAIN trials appear
Sign up with your email to follow new studies for METASTATIC MALIGNANT NEOPLASM IN THE BRAIN, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
Genom att skicka in godkänner du våra Användarvillkor
-
Experimental combo targets incurable esophageal cancer
Disease control OngoingThis early-phase study tested a drug called adavosertib combined with radiation therapy for people with advanced esophageal or stomach cancer that cannot be surgically removed. The goal was to find the safest dose and see how well the combination works. Only 4 people took part, s…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 09:02 UTC
-
New hope for lung cancer patients with brain tumors?
Disease control OngoingThis study tested whether adding a second drug (bevacizumab) to the standard targeted therapy (osimertinib) helps control lung cancer that has spread to the brain. It involved 5 adults with a specific gene mutation (EGFR) whose cancer had not been treated with similar drugs befor…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:56 UTC
-
Immunotherapy-Radiation combo shows promise for brain metastases in lung cancer
Disease control OngoingThis study is for people with advanced non-small cell lung cancer that has spread to the brain. It tests whether adding immunotherapy drugs (nivolumab, with or without ipilimumab) to radiation therapy can better control the cancer. The goal is to find the safest dose and see if i…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:53 UTC
-
New drug combo targets Hard-to-Treat lung cancer
Disease control OngoingThis early-phase trial tests two experimental drugs, sapanisertib and telaglenastat, in people with advanced non-small cell lung cancer that has spread to the brain or other areas. The goal is to find the safest dose and see if the combination can shrink tumors or slow the diseas…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:52 UTC
-
New drug combo targets breast cancer in the brain
Disease control OngoingThis study tests a drug called sacituzumab govitecan in 44 people with HER2-negative breast cancer that has spread to the brain. The drug works like a smart bomb, attaching to a protein on cancer cells and delivering chemotherapy directly to them. The goal is to see if it can shr…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 26, 2026 08:35 UTC
-
Triple threat: new drug cocktail targets tough melanoma
Disease control OngoingThis study tests whether combining three drugs—an immunotherapy (nivolumab) with two targeted therapies—can shrink or control advanced melanoma that has spread or can't be removed. It includes people with a specific gene mutation (BRAF V600) whose cancer got worse after prior tre…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
-
One big dose or several small ones? new trial tests best radiation for brain metastases
Disease control OngoingThis study looks at two ways of giving radiation after surgery to remove cancer that has spread to the brain. One method gives a single, strong dose of radiation, while the other gives several smaller doses over time. The goal is to see which approach better prevents the cancer f…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
-
Brain tumor trial tests timing of radiation to prevent return
Disease control OngoingThis study tests whether giving radiation before surgery for brain metastases is better than after surgery. It includes 237 adults with 1-4 brain tumors, one of which needs removal. The goal is to see if pre-surgery radiation lowers the chance of tumors coming back or spreading, …
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
-
New hope for brain metastases: targeted radiation may control tumors and save memory
Disease control OngoingThis study looks at whether a focused, one-time radiation treatment called stereotactic radiosurgery (SRS) can control melanoma that has spread to more than 3 spots in the brain, while also protecting memory and thinking skills. About 49 adults with advanced melanoma and multiple…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
-
Brain cancer breakthrough? new radiation after surgery may stop tumors from coming back
Disease control OngoingThis study tests whether a precise type of radiation (stereotactic radiosurgery) given after surgery for brain metastases can prevent tumors from returning better than just watching and waiting. About 132 patients with up to 3 brain tumors will be randomly assigned to receive the…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
-
Personalized medicine takes on brain tumors: Gene-Targeted drugs show promise
Disease control OngoingThis study tests whether genetic testing can help doctors choose the right drug for people whose cancer has spread to the brain. Researchers will look for specific gene changes in tumor samples and then give patients a targeted medication matched to their mutation. The goal is to…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
-
New drug cocktail shows promise for deadly brain tumors in melanoma patients
Disease control OngoingThis study tests whether combining two or three drugs can shrink or control melanoma that has spread to the brain. The drugs work by blocking tumor growth and helping the immune system attack cancer cells. The trial involves 29 adults with untreated brain metastases and aims to s…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
-
New study aims to find better radiation option for brain metastases
Disease control OngoingThis study compares two radiation treatments for people whose cancer has spread to the brain (but not from melanoma). One is stereotactic radiosurgery, which targets tumors precisely with a high dose. The other is whole brain radiation, which treats the entire brain with lower do…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
-
Engineered immune cells target brain tumors in early trial
Disease control OngoingThis early-phase study tests a new treatment called HER2-CAR T cells for people with HER2-positive cancers that have spread to the brain or its lining. The treatment involves taking the patient's own immune cells, modifying them to recognize and attack HER2-positive cancer cells,…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 11, 2026 20:47 UTC
-
Focused brain radiation may spare thinking skills in lung cancer patients
Symptom relief OngoingThis study looks at whether using a precise, targeted form of radiation (stereotactic radiosurgery) instead of whole-brain radiation can help preserve brain function in people with small cell lung cancer that has spread to the brain. About 55 participants with up to 10 brain tumo…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 09:03 UTC
-
Brain boost: new study tests cognitive care for cancer patients
Symptom relief OngoingThis study tests whether early visits with a neuropsychologist can help people with cancer that has spread to the brain maintain their quality of life after radiation therapy. About 110 adults with stage IV solid tumors and brain metastases will receive neuropsychological evaluat…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 09:00 UTC
-
New drug combo aims to boost radiation for brain tumors from lung cancer
Symptom relief OngoingThis early-phase trial tests a drug called berzosertib combined with whole brain radiation for people with lung cancer that has spread to the brain. The main goal is to find the safest dose and check for side effects. About 15 adults with non-small cell, small cell, or neuroendoc…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated May 26, 2026 08:57 UTC
-
New combo therapy for brain tumors shows promise in early trial
Symptom relief OngoingThis early-stage study tested the safety and best dose of the drug trametinib when given with or without whole-brain radiation for people with cancer that has spread to the brain. Ten participants were enrolled. The goal was to find the highest safe dose and see how much drug rea…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated May 26, 2026 08:55 UTC
-
Couples tackle brain tumors together: online program boosts Well-Being
Symptom relief OngoingThis study tests an online mind-body program for people with brain tumors (glioma or cancer spread to the brain) and their partners. The program aims to improve spiritual well-being, sleep, mood, and overall quality of life. About 74 couples will participate to see if the program…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 08:54 UTC
-
Could a simple pill boost Radiation's power against brain cancer?
Symptom relief OngoingThis early-phase study tests an oral drug called ropidoxuridine (IPdR) given alongside whole brain radiation for people whose cancer has spread to the brain. The goal is to see if the drug can make radiation work better by sensitizing tumor cells, while checking for side effects.…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated May 19, 2026 11:48 UTC
-
Brain mapping tool could prevent nerve damage during radiation
Knowledge-focused OngoingThis study looks at whether a non-invasive brain-mapping technique called nTMS can help doctors plan radiation more safely for people with brain tumors near the motor cortex (the area that controls movement). About 22 adults who already had radiation for brain tumors will undergo…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC