New combo therapy targets brain metastases in early trial
NCT ID NCT02015117
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 26 times
Summary
This early-phase study tests the safety and best dose of the drug trametinib when given with or without whole-brain radiation for people whose cancer has spread to the brain. The goal is to see if the combination is safe and how much drug reaches the brain. Only 10 participants are enrolled, and the study is no longer recruiting.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
Conditions
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