New combo therapy aims to shrink brain tumors
NCT ID NCT02015117
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 25 times
Summary
This early-stage trial tests the safety and best dose of the drug trametinib when given with or without whole-brain radiation for people with cancer that has spread to the brain. The drug blocks certain enzymes that help cancer cells grow, and radiation uses high-energy X-rays to kill tumor cells. The goal is to find a treatment that controls brain metastases with manageable side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
Conditions
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