Mental disorders

This study tested an experimental drug called XPro1595 in 208 people with early Alzheimer's disease who also had signs of brain inflammation. The goal was to see if the drug could improve memory, thinking, and daily function compared to a placebo over 24 weeks. Researchers also c…

This trial tests whether a structured lifestyle program—combining exercise, healthy eating, cognitive training, and social activities—can slow cognitive decline in older adults at risk of dementia. Participants aged 60-80 with modifiable risk factors will be randomly assigned to …

This study looks at whether Tai Chi, a gentle moving meditation, can improve chronic insomnia in breast cancer survivors. About 90 women who have completed cancer treatment and have had trouble sleeping for at least 6 months will practice Tai Chi. Researchers will measure sleep q…

This study tested whether therapeutic horseback riding can improve behavior, social skills, and emotional control in 250 autistic youth who also have a mental health condition. Participants were randomly assigned to riding, barn activities without riding, or a hybrid group. Resea…

This study tested a program based on Acceptance and Commitment Therapy (ACT) for 64 caregivers of people with mental disorders. The program aimed to help caregivers build psychological resilience, manage stress better, and feel less burdened. Results showed that those who took pa…

This study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…

This study tested whether a non-invasive brain stimulation technique called tDCS can help people with schizophrenia whose symptoms persist despite medication. 141 adults received either real or sham tDCS over 10 sessions. The goal was to see if active stimulation leads to a meani…

This study tested whether an AI-powered smartwatch could help teenagers and young adults with mental health conditions stick to their medication schedule. Researchers compared medication adherence in 78 people who wore the watch to those who did not. The goal was to see if the wa…

This study explores whether two non-invasive measures—fat in the liver and thickness of the carotid artery—can serve as early warning signs of heart and metabolic problems in children treated with antipsychotic medications. Researchers will compare these measures in children on a…

This pilot trial tests whether adding social contact — personal stories and interactions with people who have mental illness — to standard mental health training can reduce stigma among primary care workers in Nepal. About 88 healthcare providers and their patients will take part…

This study looked at the mental health of hospital staff and medical students after the 2016 Nice terrorist attack. Researchers surveyed 804 people to understand how the event affected them and to find better ways to support caregivers in future crises. The goal was to learn, not…

This study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair and accurate …