MENINGIOMA

This study tests a drug called Lutathera, which delivers radiation directly to meningioma tumor cells. It involves 32 adults with progressive or high-risk meningioma who receive four doses over 8 weeks. The main goal is to see if the treatment can stop tumor growth for at least 6…

This study tests whether a higher dose of proton radiation can safely control high-grade meningiomas, which are aggressive brain tumors. About 21 adults with specific tumor types after surgery will receive intensity-modulated proton therapy (IMPT). The goal is to find the highest…

This study looks at how well the drug ribociclib gets into brain tumors in people with recurrent high-grade glioma or meningioma. About 48 participants will take the drug before their scheduled tumor removal surgery. The goal is to measure drug levels in the blood, spinal fluid, …

This study is testing a new type of PET/CT scan that uses a special tracer (68Ga-DOTATOC) to find neuroendocrine tumors and other related cancers. The goal is to see if this scan is safer and more sensitive than current imaging methods. About 800 people with known or suspected tu…

This study was designed to test the drug ONC201 in people with a type of brain tumor called meningioma that had come back or wasn't responding to other treatments. The plan was to measure how much drug gets into the tumor during surgery and how long it keeps the tumor from growin…

This study tracks 328 adults who receive a special patch called Neuro-Patch during brain or spine surgery. The goal is to see how often complications happen and how easy the patch is for surgeons to use. No new treatment is tested—just careful observation of real-world results.

This study follows 400 adults who had skull base surgery through the nose. Researchers will measure quality of life and nose function for 2 years after surgery. The goal is to understand how modern surgical techniques affect long-term recovery and daily living.