LYMPHOMA

This early-stage study tested a drug called ALRN-6924 in 142 people with advanced solid tumors or lymphomas that have a normal p53 gene. The main goals were to check safety and find the best dose. Researchers also looked for signs that the drug could shrink tumors. The study is n…

This early-phase trial tested an experimental drug called CUDC-907 in 26 children and young adults (ages 1-21) whose solid tumors, brain tumors, or lymphoma had stopped responding to standard treatments. The main goal was to find safe dosing and identify side effects. Researchers…

This study looked at whether using telemedicine (remote doctor visits) can help people with aggressive lymphoma get the right amount of chemotherapy on time. Researchers compared patients who used telemedicine support to those who did not, measuring how much of the planned treatm…

This study tested whether adding an experimental drug (VIC-1911) to standard medications can prevent graft-versus-host disease (GVHD) and relapse in adults with blood cancers like leukemia or lymphoma who receive a stem cell transplant. Sixteen participants were enrolled. The goa…

This early-stage study tested an experimental drug, MK-1454, given as a shot into tumors, either alone or with the immunotherapy pembrolizumab. The goal was to find the safest dose and see if the combination could shrink tumors in people with advanced solid tumors or lymphomas. 1…

This study tested whether the drug dasatinib can help control chronic lymphocytic leukemia (CLL) in 17 people who had already tried other treatments. Researchers measured how many patients had their cancer shrink or disappear. The goal was to manage the disease, not cure it.

This study tested a drug called vorinostat in 56 people with certain types of lymphoma (follicular, other indolent B-cell, or mantle cell) that had returned or stopped responding to prior treatments. The main goal was to see how many patients had their tumors shrink or disappear,…

This study tested two different treatments for people newly diagnosed with a slow-growing type of lymphoma. Both treatments combined standard chemotherapy with a special antibody that targets cancer cells. The goal was to see which combo helped people live longer without their ca…

This study tested a two-step treatment for adults aged 65 to 80 with a type of lymphoma. First, they received standard chemotherapy plus a targeted antibody (rituximab). Then, they got more rituximab and a radioactive antibody (Y90 ibritumomab) to kill remaining cancer cells. The…

This study tested a strong chemotherapy combination followed by a stem cell transplant in 25 people with HIV and lymphoma. The goal was to see if the treatment is safe and possible. Participants had to be on HIV medications to keep the virus under control. The study focused on si…

This study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. The approach uses a drug called cyclophosphamide to lower the chance of graft-versus-host disease (GVHD), a serious side effect. The goal was to help more patient…

This study tested a drug called brentuximab vedotin in 50 adults with a rare type of blood cancer (systemic anaplastic large cell lymphoma) that had returned or not responded to at least one round of chemotherapy. The goal was to see how many patients had their tumors shrink or d…

This early-phase trial tested the safety of a drug called duvelisib when given with either romidepsin or bortezomib for people with T-cell lymphoma that had come back or stopped responding to treatment. The study involved 114 adults and aimed to find the safest dose. While not a …

This study tested a special stem cell product called NiCord, made by growing cord blood cells in a lab to increase their number. It was compared to standard cord blood transplants in 125 people with blood cancers like leukemia and lymphoma. The goal was to see if NiCord could hel…

This early-phase study tested a new drug called LY3039478 in 247 adults with advanced or metastatic cancer, including lymphoma. The main goals were to find a safe dose and to see how the drug affects the body and tumors. While the study looked for signs of tumor shrinkage, it pri…

This study tested a three-drug combination (VIP152, venetoclax, and prednisone) in 8 adults with aggressive non-Hodgkin lymphomas that had not responded to or returned after prior treatment. The main goals were to check safety and find the best dose. Participants took pills at ho…

This study looked at whether eating less fat and more fiber can lower the chance of a repeat Clostridioides difficile infection in people being treated for cancer. Eight patients with leukemia, lymphoma, or other cancers who had a recent C. diff infection took part. Researchers t…

This study tested an experimental tablet called XNW5004 in 120 adults with advanced tumors or lymphoma that had come back or stopped responding to standard treatments. The main goals were to check the drug's safety and find the best dose. Researchers also looked at how the drug m…

This study tested whether adding the drug bortezomib to a standard chemotherapy and antibody combination (BCVP-R) could improve outcomes for people with advanced follicular non-Hodgkin lymphoma who had not yet received treatment. A total of 95 participants were enrolled to see ho…

This study tested a new type of stem cell transplant for children and young adults (ages 2-21) with cancers that came back or didn't respond to treatment. The approach uses a special cell filter to speed up immune recovery after transplant. The main goal was to see if the procedu…

This study tested a new way to help people with blood cancers like leukemia and lymphoma get hospice care earlier. Normally, patients delay hospice because they need blood transfusions for symptom relief, but hospices can't afford to provide them. The study paid for transfusions …

This study tested a web-based program to help children aged 8-17 with cancer (like leukemia or lymphoma) return to school. The program aimed to reduce social anxiety, improve coping skills, and boost school readiness. Twenty children and their parents took part, and the program w…

This study tested a pain management program for 51 cancer survivors living in rural areas or who are Hispanic. The goal was to see if the program was easy to use and helpful for controlling cancer-related pain. Researchers measured how often participants used the program and how …

This study looked at how a common type of chemotherapy (anthracycline) affects blood vessels and blood pressure control in people treated for breast cancer or lymphoma. Researchers measured artery stiffness and blood vessel function in 60 participants, including those currently o…

This study looked at whether a care plan led by a geriatrician and a trained nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

This study looked at proteins inside lymphoma cells to better understand how the disease works. Researchers used leftover tissue samples from 130 people with lymphoma or related conditions. They measured different proteins and chemical modifications to find patterns linked to spe…

This study looked at the safety of a drug called Rituximab Pfizer in over 2,700 people in Japan with a type of lymphoma. Researchers checked how often infections and other side effects happened after treatment. They compared these results to those from patients who took a similar…

This study tested a new ultrasound technique to see the smallest blood vessels in lymph nodes on the neck. Researchers wanted to know if this method could help tell healthy lymph nodes apart from cancerous ones. Twenty adults with head and neck cancer, lymphoma, or healthy volunt…

This study followed 127 people with diffuse large B-cell lymphoma who were treated with a common chemotherapy regimen called R-CHOP. The main goal was to track heart-related side effects caused by the chemotherapy drug doxorubicin. Researchers measured how often heart problems oc…

This study followed 44 adults with leukemia or lymphoma who received CAR T-cell therapy to see how their hearts were affected. Researchers used heart scans, blood tests, and quality-of-life surveys to track heart function over time. The goal was to find out how often heart proble…

This completed study looked at 126 adults aged 60 and older who had a bone marrow transplant for blood cancers like leukemia or lymphoma. Researchers measured physical abilities, mental health, and stress levels before and after transplant to find traits that help people recover …

This study tested a program designed to help adolescent and young adult cancer survivors (ages 15-39) find healthcare resources, learn self-care skills, and get support. The goal was to see if the program could reduce cancer-related distress and help survivors follow recommended …

This study looked at whether a home-based exercise program is practical for people aged 65 and older with lymphoma, leukemia, or myeloma who are about to receive CAR-T cell therapy. Twenty participants were asked to do supervised resistance training and moderate aerobic exercise.…

This study looked at whether telehealth education and care plans created by patients themselves can help cancer survivors living in rural areas. 261 adults who finished treatment for breast, colorectal, lung, prostate cancer, or lymphoma took part. The goal was to see if these to…

This study tested a new type of PET scan (called RGD-K5) to see how blood vessels in lymphoma tumors change after two rounds of chemotherapy. Twenty-one adults with large B-cell lymphoma and a tumor mass larger than 3 cm took part. The goal was to learn more about tumor blood ves…