LIVER CIRRHOSIS

This study looks at whether giving pantoprazole (a stomach acid reducer) for a short time after endoscopic treatment for varices can lower the risk of bleeding in people with cirrhosis. About 208 adults with cirrhosis and enlarged veins in the esophagus or stomach will take part.…

This study tests if ambrisentan, a drug already used for lung blood pressure, can help people with hepatorenal syndrome—a serious kidney problem that can happen in advanced liver disease. About 54 adults will get either ambrisentan or the standard treatment terlipressin while in …

This study looks at whether the antiviral drug Bulevirtide can reduce high blood pressure in the liver (portal hypertension) in people with hepatitis B and D who also have liver cirrhosis. High liver pressure can lead to serious problems like bleeding. The study will measure live…

This study compares a shorter, faster MRI scan to the standard ultrasound for detecting liver cancer in 820 adults with liver cirrhosis. Researchers will also check if blood markers can help spot cancer. The goal is to see if the abbreviated MRI is more accurate and cost-effectiv…

This study is testing whether a new blood test, called the GAAD score, can improve the detection of liver cancer in people who are at high risk, such as those with cirrhosis or chronic hepatitis. Around 2,100 participants will get an ultrasound and the GAAD blood test every six m…

This study follows 24 adults with liver cirrhosis who recently had a sudden worsening (decompensation) requiring hospital care. Researchers will track their health over time, including lab results and major events like death or transplant. The goal is to better understand the nat…

This study looks at why people with severe liver disease (cirrhosis) who are in the intensive care unit (ICU) are at risk for a serious fungal lung infection called invasive pulmonary aspergillosis. Researchers will study 450 patients to find out how common this infection is, wha…

This study looks back at the medical records of 624 people with liver cirrhosis who had a procedure called TIPS, which helps reduce pressure in the liver. The goal is to create a simple tool that doctors can use before the procedure to predict who might develop a brain condition …

This study looks at why some people with liver cirrhosis develop a blood clot in the main vein of the liver (portal vein thrombosis). Researchers will examine medical records and imaging from 240 adults to identify patterns and risk factors. The goal is to better predict and mana…

This study tests whether sending mailed invitations and assigning patient navigators can increase the number of people who attend regular liver cancer (HCC) ultrasound screenings. The study includes 652 adults with liver cirrhosis or chronic hepatitis B who are at high risk for l…