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New tool aims to predict brain risks after liver shunt procedure

NCT ID NCT07437638

Knowledge-focused Sponsor: The Second Affiliated Hospital of Chongqing Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks back at medical records of 624 adults with liver cirrhosis who had a procedure called TIPS to relieve pressure in the liver. The goal is to create a simple tool that helps doctors predict which patients are at high risk for a brain complication called hepatic encephalopathy after the procedure. By identifying high-risk patients beforehand, doctors can take steps to prevent or manage this complication.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

624 people

The number who actually took part.

Started

Sep 2024

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This retrospective study included 624 patients with liver cirrhosis who underwent TIPS at the Second Affiliated Hospital of Chongqing Medical University between May 2011 and December 2021

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-80 years, regardless of gender * Diagnosis of decompensated cirrhosis meeting clinical guidelines * Complete preoperative baseline data available, with regular postoperative follow-up for at least 3 months to assess endpoint events * Absence of absolute contraindications for TIPS Exclusion Criteria: * Age \< 18 or \> 80 years * Non-cirrhotic portal hypertension * Hepatocellular carcinoma or other systemic malignancies * Severe cardiopulmonary disease * Prior liver transplantation or portosystemic shunt surgery * Death or liver transplantation within 30 days post-TIPS * Missing key baseline data or loss to follow-up

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis hepatic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hepatic encephalopathy Liver cirrhosis TIPS

Contacts and locations

Locations

  • Chongqing

    Chongqing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.