LIPEDEMA
Clinical trials for LIPEDEMA explained in plain language.
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Massage machine may speed recovery after lipedema surgery
Symptom relief CompletedLipedema is a painful fat condition in women's legs. Liposuction can help, but recovery often involves swelling and pain. This study tested whether adding Endermologie—a gentle suction and rolling massage—to standard physiotherapy improves recovery. 88 women took part, comparing …
Matched conditions: LIPEDEMA
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 23, 2026 22:02 UTC
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Keto diet shows promise for painful leg fat disorder in women
Symptom relief CompletedThis study looked at whether a 7-month low-carb, high-fat (ketogenic) diet could improve symptoms and quality of life in 121 women with lipedema, a chronic fat tissue disorder causing painful leg swelling. Participants followed the diet and were monitored for changes in leg size,…
Matched conditions: LIPEDEMA
Phase: NA • Sponsor: Wroclaw Medical University • Aim: Symptom relief
Last updated Jun 18, 2026 11:53 UTC
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Ozone treatment shows promise for lipedema pain
Symptom relief CompletedThis study tested whether ozone therapy can reduce pain and tissue thickness in women with lipedema, a condition that causes painful fat buildup in the legs. 45 women received either local or systemic ozone treatments. The goal was to see if ozone's anti-inflammatory effects coul…
Matched conditions: LIPEDEMA
Phase: NA • Sponsor: Ankara Etlik City Hospital • Aim: Symptom relief
Last updated Jun 11, 2026 12:11 UTC
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New study explores hidden metabolic differences between lipedema and obesity
Knowledge-focused CompletedThis study looked at 140 women to compare metabolic risk markers—like insulin resistance and cholesterol ratios—between those with lipedema and those with obesity. Researchers used existing blood test results to calculate these markers without any new treatments or interventions.…
Matched conditions: LIPEDEMA
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC
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New biorepository aims to solve lipedema misdiagnosis mystery
Knowledge-focused CompletedThis study created a biorepository (a collection of blood and tissue samples) to help researchers better understand lipedema, a painful fat disorder often mistaken for obesity. 60 women with and without lipedema provided samples and underwent tests like walking and grip strength …
Matched conditions: LIPEDEMA
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:05 UTC
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Heavy water sheds light on painful fat disorder
Knowledge-focused CompletedThis study looked at how fat cells grow in women with lipedema, a condition that causes painful fat buildup in the legs. Seventeen women drank heavy water so researchers could track new fat cell formation. The goal was to better understand what makes lipedema different from regul…
Matched conditions: LIPEDEMA
Sponsor: Pennington Biomedical Research Center • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:04 UTC
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Lipedema's hidden toll: new study reveals muscle weakness and pain
Knowledge-focused CompletedThis study looked at 30 women—half with lipedema and half without—to understand how the condition affects muscle strength, endurance, leg function, aerobic fitness, pain sensitivity, and swelling. Researchers used simple tests like walking and sitting to measure differences. The …
Matched conditions: LIPEDEMA
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:04 UTC
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Lipedema study reveals why women struggle to stay active
Knowledge-focused CompletedThis completed study looked at how lipedema affects exercise habits and physical activity in women. Researchers compared 119 women with and without lipedema, using questionnaires to measure activity levels, exercise behavior stages, and perceived barriers like fatigue or body ima…
Matched conditions: LIPEDEMA
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:57 UTC
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New ultrasound method may spot lipedema earlier
Knowledge-focused CompletedThis study tested a special ultrasound technique called shear wave elastography to see if it can measure tissue stiffness in women with lipedema, a painful fat disorder. Researchers compared 95 women with and without lipedema to find differences in leg and belly fat stiffness. Th…
Matched conditions: LIPEDEMA
Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:06 UTC
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Lipedema pain mystery: new study probes Brain's role
Knowledge-focused CompletedThis study looked at how the nervous system may become overly sensitive (central sensitization) in women with lipedema, a condition causing painful fat buildup in the legs. Researchers compared 60 women with lipedema to healthy controls, measuring pain, anxiety, depression, and p…
Matched conditions: LIPEDEMA
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC