Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Heavy water sheds light on painful fat disorder

NCT ID NCT05394467

Knowledge-focused Sponsor: Pennington Biomedical Research Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how fat cells grow in women with lipedema, a condition that causes painful fat buildup in the legs. Seventeen women drank heavy water so researchers could track new fat cell formation. The goal was to better understand what makes lipedema different from regular obesity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

17 people

The number who actually took part.

Started

Apr 2022

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Women with diagnosed lipedema will be recruited and enrolled at Pennington Biomedical Research Center. A racially/ethnically diverse population will be recruited based on the local demographics

Ages

18 to 45 years

Sex

Female participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * BMI ≤50 kg/m2 * Waist/hip ratio \<0.86 (standing position) * Clinical diagnosis of lipedema (mostly Stage 3 but Stage 2 will not be excluded) * Willing to drink deuterated water (2H2O) Exclusion Criteria: * Have major organ disease (heart, kidney, lung, thyroid, liver) or abnormal liver enzymes that represent a problem for study inclusion * Chronic use of systemic glucocorticoids, atypical anti-psychotic medications, or medications that cause clinically significant changes in weight * Pregnancy or breastfeeding in the next 3 months * Partial and/or full hysterectomy (due to estrogen effects on adipogenesis) * PCOS * Self-reported positive test for HIV, hepatitis B and hepatitis C * Smoking or use of tobacco products in the last 6 months * Any medical, psychiatric or behavioral factors that may interfere with study participation

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Lipedema are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Lipedema Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lipedema

Contacts and locations

Locations

  • Pennington Biomedical Research Center

    Baton Rouge, Louisiana, 70808, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.