LIPEDEMA

This study uses special ultrasound techniques to find clear differences between lymphedema and lipedema, two chronic conditions that cause leg swelling and are often hard to tell apart. Researchers will compare 75 adults—those with lymphedema, those with lipedema, and healthy vol…

This study tests two non-invasive treatments—ultrasound fat cavitation and pneumatic compression—to see which better reduces fat thickness in women with mild to moderate lipedema. Lipedema is a painful fat disorder affecting millions of women. The goal is to find a safe, surgery-…

This study looks at whether women with lipedema have more foot problems, like flat feet, and looser joints compared to women without the condition. Researchers will use foot X-rays and flexibility tests to measure differences. The goal is to better understand how lipedema affects…

This study investigates whether women with lipedema, a chronic fat disorder causing pain and swelling in the legs, also have a condition called central sensitization—where the nervous system becomes overly sensitive to pain. Researchers will compare 50 participants (25 with liped…

This study looks at how metabolic factors like insulin resistance and body measurements relate to pain and nerve sensitivity in women with lipedema. Researchers will measure pain levels and central sensitization (a condition where the nervous system is overly sensitive to pain) i…

This study is creating a collection of blood, urine, and stool samples from 500 adults with or at risk for heart and blood vessel diseases. Researchers will use these samples to study inflammation, blood clotting, and other biological pathways. The goal is to build a resource tha…