LEUKEMIA

This study tested the drug eltrombopag in 9 people who had poor graft function after a stem cell transplant for leukemia. Poor graft function means the new donor cells don't make enough blood cells, leading to low platelets and other issues. The goal was to see if eltrombopag cou…

This study tested whether combining two drugs, CB-103 and venetoclax, could help control T-cell acute lymphoblastic leukemia (T-ALL) in teens and young adults whose cancer had come back or stopped responding to treatment. Only 2 people enrolled before the trial was stopped early.…

This study tested the drug ponatinib in 51 adults with a fast-growing form of chronic myeloid leukemia (CML) who had little or no prior treatment. The goal was to see if ponatinib could control the disease by blocking a protein that drives leukemia growth. However, the drug can c…

This study tested whether the drug ofatumumab could control any remaining chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) after initial chemotherapy. It was designed for patients whose disease had not worsened after prior treatment. The trial was terminated…

This study tested a two-drug combination (ibrutinib followed by ibrutinib plus venetoclax) in 30 adults with chronic lymphocytic leukemia (CLL) that had returned or stopped responding to prior treatment. The goal was to see if the drugs could clear the disease from the blood and …

This study tested a new cell therapy called GDX012 in 16 people with acute myeloid leukemia that had come back or not responded to treatment. The main goals were to check safety and find the best dose. The trial was stopped early, but results help guide future research.

This study tested whether adding ponatinib to standard chemotherapy and venetoclax could help people with T-cell acute lymphoblastic leukemia that came back or didn't respond to prior treatment. Only 4 people enrolled before the study was stopped early. The goal was to see how ma…

This study tested a digital app that appears on the phone's lock screen to encourage physical activity in cancer survivors. Participants used the app for 3 months and wore a Fitbit to track activity. The goal was to see if the app could increase exercise and improve blood vessel …

This research registry looks at the health, well-being, and needs of people who survived cancer as young adults (diagnosed between ages 18 and 39). It tracks levels of anxiety, depression, social support, and financial distress by having participants fill out online surveys every…

This early-stage study aimed to see if an oral (pill) form of the chemotherapy drug cladribine works similarly to the standard IV (intravenous) version in people with certain blood cancers like leukemia. Only 3 people took part before the study was stopped early. The main goal wa…