LEUKEMIA

This study tests two weight management programs for children and teens who have had leukemia. About 80 kids and their caregivers will join one of two programs: a basic educational program or a more guided family-based approach. The goal is to help survivors avoid unhealthy weight…

This study tests a new combination of chemotherapy and immunotherapy drugs for adolescents and young adults (ages 15-39) with newly diagnosed Philadelphia chromosome-negative acute lymphoblastic leukemia (ALL). The goal is to see if this treatment plan helps more patients complet…

This study tests a stem cell transplant approach for people with blood cancers caused by an inherited RUNX1 gene mutation. The goal is to see if customizing chemotherapy and supportive care doses for each patient improves disease-free survival compared to standard transplant outc…

This early-phase study tests whether adding a new drug called eganelisib to two standard AML treatments (venetoclax and azacitidine) is safe for people with acute myeloid leukemia that has come back or not responded to prior therapy. About 48 adults will take part to find the bes…

This study tests a new drug called BT02 in people with blood cancers (leukemia, lymphoma, or multiple myeloma) that have returned or not responded to treatment. About 116 adults aged 18 to 70 will receive the drug by IV every 2-3 weeks for up to 2 years. The main goals are to che…

This study will create a structured follow-up program for 400 children and young adults who have survived blood cancers like leukemia and lymphoma. The goal is to better track and manage long-term health problems that can appear years after treatment. Researchers will use an elec…

This study will follow 5,000 adults who have immune system problems (like inflammation or autoimmune disease) to see how often they also develop blood disorders, including a rare condition called VEXAS syndrome. Researchers will track new cases over time to better understand the …