New study aims to help childhood leukemia survivors fight weight gain
NCT ID NCT07374315
First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This study compares two weight management programs for children who have had acute lymphoblastic leukemia (ALL). About 80 children and their caregivers will be randomly assigned to either a basic educational program or a more intensive guided self-help program. The goal is to see which approach better helps children maintain a healthy weight and improve overall health after cancer treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- behavioral intervention (weight management programs)
- What this could lead to
- If successful, this could provide an effective way to help childhood leukemia survivors maintain a healthy weight and reduce long-term health risks.
- What could go wrong
- This is a small, early-stage trial with only 80 participants, so results may not apply to everyone. The programs require family commitment and may not work for all.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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May 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Patient Eligibility Criteria: * Must have a diagnosis of ALL (T or B cell). * Must be receiving standard of care maintenance chemotherapy or be within 6 months of having concluded maintenance chemotherapy at the time of enrollment. * Must be at least 6 years of age and no older than 18 years of age at time of enrollment. * Must be able to speak and understand English. * Must have a caregiver who is participating in this study. * Must be able to perform some level of exercise (e.g., a brisk walk for at least five minutes) as determined by self-report. * Must not have severe developmental delay/intellectual disabilities (such as Trisomy32, severe presentations of autism spectrum disorder) or significant mental illness (such as active suicidal ideation, psychotic symptoms, manic or hypomanic episodes, or severe substance use disorder) that may interfere with ability to participate in modified Family Based Therapy (FBT). * Patients 10 and older must have a negative SCOFF screen for disordered eating (Score of 2 or more would disqualify the patient and require discussion with primary team) * Must be able to understand and willing to sign an IRB-approved written informed consent document or be able to provide verbal assent along with written consent provided by a legally authorized representative. Caregiver Eligibility Criteria: * Self-reported as the primary caregiver of a pediatric patient diagnosed with ALL who is also participating in this study. * Must be at least 18 years of age. * Must be able to speak and understand English. * Must be able to perform some level of exercise (e.g., a brisk walk for at least five minutes) as determined by self-report * Must be able to understand willing to sign an Institutional Review Board (IRB)-approved written informed consent document.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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