KIDNEY FAILURE, CHRONIC

This study looked at 78 adults with advanced kidney failure who needed surgery to create a blood vessel connection (fistula) for dialysis. Researchers compared two ways to numb the arm during surgery: a local injection versus a nerve block near the armpit. The goal was to see if …

This study tested an experimental drug called MK-2060 in 506 people with end-stage kidney disease who need dialysis through a special tube (graft) in their arm. The goal was to see if the drug could prevent dangerous blood clots from blocking the graft. Researchers compared two d…

This study looked at whether people with kidney failure who still have some kidney function can safely dialyze only twice a week instead of the usual three times. 58 patients on hemodialysis for at least 3 months with residual kidney function took part. Researchers measured quali…

This study tested whether taking probiotics or synbiotics (probiotics plus fiber) for 6 months could improve health in 60 adults with kidney failure on dialysis. Researchers measured changes in blood toxins, heart health, quality of life, and thinking ability. The goal was to see…

This study looked at whether regularly testing and retraining new peritoneal dialysis patients on infection prevention can lower their risk of peritonitis, a serious infection of the belly lining. Over 700 adults who could do their own dialysis were split into two groups: one rec…

This study looked at how the drug MK-5684 is processed in the bodies of men with severe kidney disease or end-stage kidney disease compared to healthy men. Researchers measured drug levels in the blood over time and checked for side effects. The goal was to understand how kidney …

This study looked at how the body handles a single dose of the experimental drug BMS-986278 in people with severe kidney problems or those on dialysis, compared to healthy volunteers. The goal was to understand safety and drug levels, not to treat the disease. 27 adults took part…

This study looked at 300 kidney transplant recipients to see if a simple urine test could predict scarring in the new kidney. Researchers measured specific genes in urine cells during the first year after transplant. The goal was to find a non-invasive way to detect early damage,…

This early-phase study tested a single injection of a new drug called MK-2060 in 14 people with advanced chronic kidney disease. The main goal was to check safety and how the drug moves through the body. Only the first part was completed; later parts were not started for reasons …

This study looked at 268 adults with kidney failure who were on dialysis. Researchers used portable heart monitors to track heart rhythm problems and blood sugar changes. The goal was to see how these issues relate to the risk of heart-related death or other serious heart events …

This study tested a communication tool called "Best Case/Worst Case" to help older adults with end-stage kidney disease and their doctors talk about treatment options, including palliative care. Over 400 patients from ten kidney clinics took part, with some doctors trained to use…