Kidney failure, chronic

People on hemodialysis need their fistula punctured with a needle three times a week, which can be painful and anxiety-provoking. This trial compares three approaches: usual care, applying an ice pack to a specific point on the hand before the needle, and using a numbing gel. Res…

This study looks at how the drug eloralintide enters the bloodstream and leaves the body in people with severe kidney disease or kidney failure, compared to healthy volunteers. About 28 participants will receive a single shot under the skin. The study lasts about 14 weeks and doe…

This early study is testing whether the diabetes and heart failure drug empagliflozin (Jardiance) is safe for people on dialysis for kidney failure. The drug is already approved for other uses but has not been studied in dialysis patients. Researchers will give 24 participants ei…

This study follows 1,600 people with chronic kidney disease for 10 years to see how different types of exercise affect harmful toxins in the blood, physical fitness, and overall health. Participants include those in early stages, on dialysis, or with a kidney transplant. The goal…