Can exercise slow kidney disease? major 10-year study launches
NCT ID NCT06910475
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 1,600 people with chronic kidney disease for 10 years to see how different types of exercise affect harmful toxins in the blood, physical fitness, and overall health. Participants include those in early stages, on dialysis, or with a kidney transplant. The goal is to understand how exercise can help manage the disease and slow its progression.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 1,600 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Apr 2025
- Expected to finish
-
Dec 2035
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * those diagnosed with chronic kidney disease and presenting persistent albuminuria (\>300mg/g) following KDIGO guidelines; * metabolic syndrome {i.e., type 2 diabetes mellitus, arterial hypertension (blood pressure \>180/100mmHg), overweight or obesity, and dyslipidemia}; * no complications arising from pre-existing clinical metabolic diseases (i.e., diabetic coma, ketoacidosis, hyperosmolarity, and/or uncontrolled diabetes), as evaluated by a nephrologist; * absence of neurodegenerative, musculoskeletal, lupus erythematosus, or congenital kidney disease; * no apparent cardiovascular complications, such as heart failure, severe arrhythmia, angina, or cerebrovascular disease; * no comorbidities that limit performance in physical tests or training; * not engaged in exercise programs for at least six months prior to the start of the experimental protocol; * no smoking or alcohol consumption behavior; * D-dimer values within normal range (220-500 ng/mL FEU) Exclusion Criteria: * regularly engage in physical exercise, * have suffered a stroke in the last 6 months and/or present autoimmune diseases, * have unstable cardiac dysfunctions, such as: uncontrolled coronary artery disease, aneurysm at risk of rupture, uncontrolled arrhythmia, uncontrolled hypertension (SBP \> 190 mmHg and/or DBP \> 100 mmHg), heart attack in the last 3 months; * infectious conditions, Hb \< 8 in the last routine monthly hemodialysis exam; * musculoskeletal pain; * fever; * resting SpO2 lower than 94%; * restriction by the clinical team.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Kidney disease, chronic are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Catholic University of Brasília
Taguatinga, Federal District, 71966-700, Brazil
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Fewer dialysis sessions: can Twice-Weekly work as well?
- Does better dialysis keep parathyroid hormone in check?
- Do kidney patients know why a fistula matters before dialysis?
- Can we predict who will progress quickly to kidney failure?
- Can lowering phosphate save hearts in kidney failure?
- Can a new drug work safely in patients with kidney failure?