KIDNEY DISEASE, CHRONIC

This study tests whether a ketoanalogue supplement, taken alongside a moderately low-protein diet, can prevent muscle loss in people with stage 4 or 5 chronic kidney disease (CKD). About 100 adults will take the supplement or a placebo for several months, and researchers will mea…

This study is for men aged 18-85 with both low testosterone and chronic kidney disease. Researchers want to see if an oral testosterone medication called JATENZO can safely raise testosterone levels and improve red blood cell counts, muscle strength, and sexual function. The stud…

This study tests whether doing a genetic test before a kidney transplant can help doctors choose the best starting dose of tacrolimus, an anti-rejection drug. About 114 adults waiting for a kidney transplant will be randomly assigned to either standard care or the genetic-testing…

This study tests a new treatment called AdiaVita, made from umbilical cord stem cells and glutathione, in 100 adults with chronic kidney disease (stages 2-4). Participants receive monthly IV infusions for 3 months and use a skin spray at home. The goal is to see if the treatment …

This study compares a special egg white pudding to a standard nutritional drink (Ensure Plus) in 54 adults with kidney failure who are on dialysis. The goal is to see if the pudding is a practical way to improve nutrition, blood protein levels, and frailty. Participants will rece…

This study tests whether adding the experimental drug BI 690517 to the existing medication empagliflozin can slow kidney disease worsening in adults with chronic kidney disease. About 11,000 participants, with or without type 2 diabetes, will be randomly assigned to receive eithe…

This study looks at how a gene called APOL1 affects kidney transplant success. African Americans and others with recent African ancestry are more likely to have a risky version of this gene. Researchers will test DNA from 5000 donors and recipients to see if the gene leads to kid…

This study aims to understand how genes influence kidney disease risk. Anyone 18 or older living in the US can join, even if they don't have kidney disease. Participants fill out online health surveys and provide a saliva sample by mail. In return, they may receive free informati…

This study follows 200 kidney transplant patients in Scotland to see if certain biomarkers can help predict transplant rejection. Researchers will collect urine samples and track health outcomes during routine follow-up visits. The goal is to improve how doctors monitor and manag…