INTRACEREBRAL HEMORRHAGE

This study tests a drug called rFVIIa that helps blood clot, given within 2 hours of a bleeding stroke. The goal is to stop the bleeding and improve recovery at 90 days. About 350 adults aged 18-80 with a specific type of brain bleed are being recruited. The drug is compared to s…

This study compares two blood thinners—apixaban and aspirin—in people who have had a brain bleed (intracerebral hemorrhage) and also have an irregular heartbeat (atrial fibrillation). The goal is to see which drug better prevents another stroke or death. About 700 adults will tak…

This study tests whether a mobile health app can help people who have had a bleeding stroke (intracerebral hemorrhage) better control their blood pressure. High blood pressure is a major risk factor for another stroke. The study will enroll 140 participants and track blood pressu…

This study tests whether using AI to guide a minimally invasive surgery to remove a brain bleed leads to better recovery than medication alone. About 680 adults with moderate-sized bleeds will be randomly assigned to one of the two treatments. The goal is to see which approach re…

This study looks at whether a dedicated care plan can help people who have a non-traumatic brain hemorrhage (a type of stroke). The plan focuses on fast, expert care in specialized hospital units. Researchers will track 600 patients to see if the plan reduces death and long-term …

This study tests whether the antibiotic minocycline can improve recovery in people who have had a brain bleed (intracerebral hemorrhage). About 1,200 adults will receive either minocycline or a placebo within 48 hours of their stroke. The goal is to see if the drug helps more peo…

This study tests whether a drug called clevidipine can lower blood pressure quickly and keep it stable in people having a bleeding stroke. About 1,000 adults with high blood pressure and stroke symptoms will receive either clevidipine or another IV blood pressure medicine. The go…

This study tests whether a mild electrical stimulation applied to the ear (called taVNS) can safely reduce brain swelling in people who recently had a bleeding stroke. 186 adults with moderate bleeding will be randomly assigned to receive either real or fake stimulation. The main…

This study tests whether the drug tranexamic acid can prevent brain bleeding from getting worse in people with a type of stroke called intracerebral hemorrhage. The researchers are using new rules to select patients most likely to benefit, based on the size and location of the bl…

This study tests whether a non-invasive ultrasound device can safely help clear blood clots in the brain after a hemorrhagic stroke. About 86 adults with small-to-medium sized bleeds will receive either standard care alone or standard care plus ultrasound treatment. The goal is t…

This study tests whether a gentle, early surgery using a thin tube (catheter) to drain a brain bleed, along with clot-busting medicine, helps people recover better than standard medical care alone. About 750 adults with a large brain bleed will be randomly assigned to one of the …

This study looks at 300 adults with atrial fibrillation (an irregular heartbeat) who have had a brain bleed. It compares three approaches to prevent future strokes: taking blood thinners, using a device to close a part of the heart, or avoiding both. The goal is to find which opt…

This study looks at whether people who had a brain bleed (intracerebral hemorrhage) should keep taking statins or stop them. It involves 1,456 adults aged 50 and older who were on statins before their bleed. The goal is to see which approach lowers the risk of another bleed and o…

This study tests whether giving a triple blood pressure pill soon after a brain bleed (intracerebral hemorrhage) helps control blood pressure better than usual care. It includes 140 adults in Hong Kong who are at high risk based on a special score. The goal is to lower the chance…

This study tests whether a simple set of treatments—lowering blood pressure, controlling fever, and managing blood sugar—can help people recover better after a brain bleed (intracerebral hemorrhage). About 3,500 adults in Sweden and Australia will receive either the care bundle o…

This study looks at 200 people with high-blood-pressure-related brain bleeding to find the best time to start blood thinners (heparin) to prevent dangerous clots in the legs or lungs. Participants get heparin either within 2 days (but not before 12 hours) or starting on day 3 aft…

This study tests whether high doses of vitamin D can help clear blood from the brain after a severe stroke. About 40 adults who recently had a bleeding stroke will receive either vitamin D or standard care. The goal is to see if vitamin D is safe and speeds up recovery.

This study looks at how the heart's performance relates to recovery in people with severe brain injuries or brain bleeds. Researchers will collect data from standard monitors already used in the ICU and follow up with participants 6 months after they leave the hospital. The goal …

This study looks at whether frequent neurological checks in the ICU disrupt sleep and worsen confusion (delirium) in older adults with a brain bleed. Researchers will compare checks every hour versus every two hours in 120 patients. The goal is to see if less frequent checks can …

This study looks at a condition called augmented renal clearance (ARC), where the kidneys work too fast and remove medications too quickly. It focuses on adults in the intensive care unit with life-threatening brain problems like stroke, severe injury, or infection. Researchers w…

This study is for adults who have had a stroke (blood clot or bleeding in the brain). Researchers want to learn why some people develop memory and thinking problems after a stroke, while others do not. They will use brain scans, blood tests, and memory tests to find clues. The go…

This study looks at how a nerve block (stellate ganglion block) changes tiny blood vessels in the eye. Researchers will use a special camera to take pictures of the retina before and after the procedure in 50 adults who are already receiving the block for pain. The goal is to und…

This study follows 500 adults who had surgery for a brain hemorrhage to see how different surgical methods affect their recovery and quality of life. Participants are aged 18 to 80 and must have had a certain type of brain bleed. The goal is to learn which treatments lead to the …

This study is testing whether a non-invasive ultrasound scan, combined with artificial intelligence, can quickly identify bleeding in the brain (intracerebral hemorrhage) in people having a stroke. About 500 adults with stroke symptoms will get an ultrasound within 48 hours, and …

This study is testing two new imaging prototypes from Siemens during minimally invasive surgery to remove brain bleeds. The prototypes aim to help doctors see how much bleeding remains after the procedure and check blood flow in the brain. About 15 adults having this surgery at M…

This pilot study is testing whether a non-invasive eye scan called OCTA can detect changes in blood flow in people with neurological conditions like stroke and brain hemorrhage. Researchers will compare scans from 50 patients and healthy volunteers to gather preliminary data. The…

This study looks at how to improve removal of blood clots in the brain after a hemorrhagic stroke. Researchers will create blood clots in the lab from people with and without bleeding risks, then test different doses of a clot-busting drug. The goal is to find the best dose for e…

This study is testing a new device that measures pressure around the brain from outside the head, avoiding the need for risky surgery. Researchers will collect data from 581 patients who already have standard surgical monitors, to help develop a safer, non-invasive alternative. T…

This study looks at whether giving antibiotics for the entire time a brain drain (EVD) is in place prevents infections better than just a single dose before placement. About 84 adults with certain brain conditions will take part. The goal is to find out if longer antibiotic use i…