INTRACEREBRAL HEMORRHAGE

This study tests whether the antibiotic minocycline can improve recovery after a type of stroke called intracerebral hemorrhage (brain bleed). About 1,248 adults will receive either standard care or standard care plus minocycline for 7 days. Researchers will check their ability t…

This early study tests whether a drug called Tenecteplase (TNK) is safe to use directly in the brain to break up clots from a brain bleed. Five adults with a large brain bleed will receive a single dose of TNK during standard surgery. The main goal is to check for side effects li…

This study tests whether combining a small surgery to remove blood clots from the brain with a drug called deferoxamine can help people recover better after a brain bleed. About 240 adults with moderate to severe bleeding will be randomly assigned to get the combo treatment or st…

This study tests a traditional Chinese medicine called Calculus Bovis Sativus (CBS) in 300 people who have had a brain hemorrhage. CBS is made from bezoar ingredients and is thought to reduce inflammation and protect brain cells. The goal is to see if it improves recovery and red…

This study tests if using a bladder thermometer to guide body temperature control helps people recover from severe brain bleeding. About 308 adults will be randomly assigned to either continuous bladder temperature monitoring or standard armpit temperature checks. The goal is to …

This study tests a handheld blood test that measures a protein called GFAP to help paramedics tell if a stroke patient has a brain bleed. About 465 adults with stroke symptoms and high blood pressure will have the test in the ambulance, and results will be checked against hospita…

This early study tests the safety and best dose of a drug called propranolol, given continuously through a vein for 7 days, to prevent pneumonia in people who have had a severe brain bleed (intracerebral hemorrhage). About 30 adults will take part. The main goal is to find a safe…

This study will collect detailed information from 200 adults with severe traumatic brain injury or other severe brain injuries treated at Örebro University Hospital. Researchers will track their health, brain scans, and recovery for up to a year to better understand how these inj…

This study aims to validate the Stroke Mimics Score, a tool that uses information collected when a patient arrives at the emergency room to help doctors quickly tell the difference between a real stroke and other conditions that mimic stroke symptoms. Researchers will enroll 1,00…

This study looks at how air moves in the lungs of brain-injured patients when doctors are trying to remove their breathing tube. Researchers will use a special imaging belt (electrical impedance tomography) to see if certain lung ventilation patterns can predict whether the tube …

This study looks at 117 adults who had a bleeding stroke (intracerebral hemorrhage). About 10 days after the stroke, they will get special brain scans and blood tests to measure inflammation and blood-brain barrier damage. The goal is to see if these measures can predict how well…

This study aims to understand if specific markers on brain scans can better predict which patients with brain hemorrhage face higher risks of death or disability. Researchers will compare scan findings with existing prediction methods in 50 participants. The goal is to improve ri…