INFLAMMATORY BOWEL DISEASE (IBD)

This study tests whether a 12-week personalized aerobic exercise program, done at home with remote guidance, can improve heart and lung fitness, control disease activity, and boost quality of life in adults with mild or inactive inflammatory bowel disease (IBD). About 28 particip…

This study tests several new investigational drugs in 140 adults with moderate-to-severe Crohn's disease or ulcerative colitis. The main goals are to check safety and see if the drugs can improve symptoms and reduce gut inflammation seen on camera exams. Participants must have a …

This study tests whether switching to a drug called guselkumab (Tremfya) can help people with inflammatory bowel disease (IBD) who did not get enough relief from ustekinumab. About 200 adults across Canada will take guselkumab for one year, and doctors will track their symptoms a…

This study is testing an upgraded nutritional drink (Elemental 028 Extra) for children and adults with severe gut conditions like inflammatory bowel disease, short bowel syndrome, or severe allergies. The drink is designed to be a complete source of nutrition when the gut cannot …

This study is testing whether a smartphone app called SMART-IBD can help teenagers (ages 13-17) with inflammatory bowel disease (IBD) take their medications as prescribed and improve their self-management skills. The app includes daily symptom diaries, medication reminders, educa…

This study looks at whether people with moderate-to-severe inflammatory bowel disease (IBD) need to routinely take dexamethasone (a steroid) before receiving infliximab to prevent allergic reactions. Researchers will compare those who get the pre-medication as usual with those wh…

This study tests whether a smartphone app called MyIBDDiet can help people with inflammatory bowel disease (IBD) learn about and follow an anti-inflammatory diet. About 40 adults with IBD who are not currently having a flare-up will use the app for one month. Researchers will mea…

This study looks at whether teaching children and teens with inflammatory bowel disease (IBD) to eat fewer ultra-processed foods (like chips, soda, and fast food) can improve their health. About 120 participants will track their eating online and receive either a handout or a han…

This study tests whether a 12-week remote exercise program can improve quality of life for adults with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Participants will use a smartphone app to follow adapted physical activities from home. The g…

This study tests an experimental drug called DISC-0974 for people with inflammatory bowel disease (IBD) who also have anemia (low red blood cells). About 21 adults with mild IBD and anemia will receive either the drug or a placebo. The main goal is to see if the drug safely raise…

This study aims to find new markers in the blood that can detect an imbalance of gut bacteria linked to inflammatory bowel disease (IBD). Researchers will compare 60 people with IBD to 60 people without the condition, collecting stool, blood, and tissue samples. The goal is to de…

This study is observing 600 adults in South Korea who are already receiving vedolizumab injections for ulcerative colitis or Crohn's disease. Researchers will look at medical records to track side effects and how well the treatment works. No new treatments are given—this is just …

This study is creating a large database of people with Crohn's disease and ulcerative colitis in Argentina. Doctors will collect information on patient demographics, treatments, and safety outcomes from routine care. The goal is to better understand how these diseases are managed…

This study is the first time PVT401, a potential treatment for inflammatory bowel disease (IBD), is being tested in humans. The goal is to see if it is safe and how the body processes it. Healthy volunteers will receive either the drug or a placebo, and researchers will monitor t…

This study follows 200 adults with Crohn's disease or ulcerative colitis who are prescribed Zymfentra as part of their normal care. Participants answer online surveys about their bowel symptoms over one year. The goal is to see if Zymfentra helps reduce symptoms and improve disea…

This study collects health information from up to 10,000 people with conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a phone app to share symptoms, wearables data, and lifestyle details. The goal is to help researchers better understand these illness…

This study looks for tiny plastic particles (microplastics) in children with and without inflammatory bowel disease (IBD). Researchers will collect samples of gut tissue, stool, urine, and blood during routine medical procedures. The goal is to see if microplastics are present an…