INFLAMMATORY BOWEL DISEASE (IBD)

This early-stage trial tests whether xylitol, a common sugar substitute, can safely clear C. difficile bacteria from the gut in people with inflammatory bowel disease (IBD). About 69 adults with mild or inactive IBD will take xylitol by mouth, and researchers will check if the in…

This study tests whether transplanting healthy stool bacteria (fecal microbiota transplantation) can improve liver function in 72 adults with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD). Participants will receive either real FMT or a sham procedure a…

This study tests a special day hospital program for people with inflammatory bowel disease (IBD), like Crohn's disease or ulcerative colitis. The program combines blood tests, doctor visits, education, and workshops in a single day. Researchers want to see if this approach helps …

This study compares two antibiotics, fidaxomicin and vancomycin, to see which one is better at clearing C. difficile bacteria from the gut in people with inflammatory bowel disease (IBD). About 60 adults with IBD will take one of the two antibiotics for 10 days, and researchers w…

This study tests whether a daily synbiotic formula (SGR11) can improve symptoms and quality of life in 50 adults with mild to moderate ulcerative colitis, a type of inflammatory bowel disease. Participants take the formula for 8 weeks and complete questionnaires and stool tests. …

This study aims to improve how we screen for colorectal cancer by using a new blood test. Researchers will look for special molecules called oncofetal chondroitin sulfate (ofCS) that appear in tumors. They will collect blood from 2000 people scheduled for a colonoscopy to see if …

This study looks at whether measuring two specific genes (NEAT1 and ANRIL) in a blood sample can help diagnose inflammatory bowel disease (IBD) without needing a colonoscopy. Researchers will enroll 62 newly diagnosed IBD patients and compare their gene levels to their symptoms a…

This study tests whether an AI-enhanced virtual reality cognitive behavioral therapy program can reduce anxiety and improve quality of life in people with inflammatory bowel disease (IBD). About 76 adults with IBD and moderate-to-severe anxiety will use either the VR therapy or a…

This study looks at a new way to control inflammation during flare-ups of Crohn's disease and ulcerative colitis. Researchers will test if tiny oxygen-filled bubbles can reprogram immune cells called monocytes to produce fewer inflammatory signals. The goal is to find a gentler t…

This study compares two ways to examine the colon in people with inflammatory bowel disease (IBD) who are at higher risk for colon cancer. One method uses a dye sprayed inside the colon, while the other uses advanced camera technology to enhance images without dye. About 480 adul…

This study looks at how being obese might change how well treatments work for people with inflammatory bowel disease (IBD), like Crohn's disease or ulcerative colitis. Researchers will follow 120 adults with IBD who are on standard treatments, including biologics, to see if those…

This study will test a new device called the Magnetic Flexible Endoscope (MFE) in 6 people with stable inflammatory bowel disease (IBD). The MFE uses a tiny camera and magnet at its tip, guided by an external robotic arm, to move through the colon. Researchers want to see if the …

This study aims to see if data from smartwatches and smartphones can detect when inflammatory bowel disease (IBD) symptoms get worse. About 80 adults with Crohn's disease or ulcerative colitis will wear a smartwatch and use an app while shopping at Colruyt stores. Researchers wil…