INFECTIONS

This study tested whether using a special antiseptic dressing (with chlorhexidine) on the tubes that connect patients to an ECMO machine can reduce serious infections. ECMO is a life-support machine for people with severe heart or lung failure. The trial involved 270 patients and…

This study looked at whether adults with acute illnesses like infections, heart failure, or COPD can be safely treated at home instead of in a hospital. 160 rural patients were randomly assigned to receive hospital-level care at home or usual hospital care. The goal was to see if…

This study tested an investigational drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if vapendavir could reduce lower respiratory symptoms like cough, wheezing, and shortness of breath after they were exposed to a common cold virus (rhi…

This study tested whether a special wound vacuum (negative pressure therapy) works better than standard stitches to prevent surgical site infections in 50 patients who had emergency abdominal surgery for peritonitis (a serious belly infection). The main goal was to see which meth…

This study tested new portable sensor platforms to quickly and cheaply detect viruses (like SARS-CoV-2), bacteria, and parasites in blood and respiratory samples. Researchers compared the sensors' accuracy to standard lab tests using samples from 149 adult patients. The goal is t…

This large study tested a new approach: using a special light treatment inside the nose just before surgery to kill germs and prevent wound infections. Over 4,700 adults having major surgeries (like heart, spine, or joint replacement) took part. The goal was to see if this simple…

This study tested a new way to prevent infections after surgery. Before their operation, 401 adults received either a nasal light treatment (photodisinfection) or standard care. The goal was to see if the light therapy could reduce surgical site infections within 30 days. The tre…

This study tested whether a supplement made from bovine colostrum (the first milk from cows) can prevent repeated urinary tract infections (UTIs) in children. Sixty children with a history of recurrent UTIs took part. The goal was to see if this natural supplement could reduce th…

This study looked at 351 adults with inguinal hernia who had keyhole surgery (TAPP). Doctors compared using 3 stitches versus 1 stitch to hold the mesh in place. The goal was to see which method caused less pain, fewer fluid collections (seroma), and fewer hernia comebacks over a…

This study looked at whether giving an antibiotic (piperacillin-tazobactam) as a longer infusion helps people with obesity reach the right drug level in their blood. It included 45 hospitalized adults with obesity who needed the antibiotic. The main goal was to see if a larger st…

This study tested a new experimental malaria drug called MMV367 in 12 healthy adults. Participants were intentionally infected with a controlled, low-level malaria infection to see how well the drug kills the parasite and how safe it is. The goal was to understand the right dose …

This study tested whether showing hospital patients a short video about how to use special CHG bathing cloths helps them follow instructions better. About 1,000 patients took part, and researchers checked if the video improved bathing compliance and reduced bloodstream infections…

This study looked at whether running an ultratrail (a very long race) increases the risk of getting sick afterward. Researchers compared 471 runners with their companions who did not run. They tracked symptoms like colds, sore throats, and fever for three weeks after the race to …