INFECTIONS

This study tested whether giving a common antibiotic (piperacillin-tazobactam) as a longer, slower infusion is a practical way to research better dosing for people with obesity. It involved 45 hospitalized adults with obesity who needed this antibiotic. The main goal was to see i…

This study tested an experimental drug called vapendavir to see if it could reduce serious lung symptoms in people with COPD after they caught a common cold virus. Researchers gave the drug or a placebo to 52 adults with moderate COPD who were then exposed to the virus. The main …

This study tested whether providing full hospital-level medical care in patients' own homes is a safe and effective alternative to traditional hospital stays for rural adults. It involved 160 adults with serious but manageable conditions like severe infections, heart failure, COP…

This study tested new portable sensor devices designed to quickly identify specific infections like COVID-19, Pseudomonas bacteria, and Leishmania parasites in patient samples. Researchers compared these new tests against standard lab methods to see if they were accurate, fast, a…

This study tested whether using a special antiseptic dressing on the tubes (cannulas) of ECMO machines could prevent serious infections. ECMO is a life-support machine used for patients with severe heart or lung failure. Researchers compared the antiseptic dressing to a standard …

This study tested whether showing patients a short educational video could help prevent serious bloodstream infections. About 1,000 hospitalized patients who needed to use special antiseptic bathing cloths participated. Researchers compared units where patients watched the video …

This study tested whether a special wound dressing (negative pressure wound therapy) could prevent infections better than standard wound closure after emergency abdominal surgery for peritonitis. It involved 50 patients who had this urgent surgery and followed them for a year. Th…

This study tested whether a daily supplement made from cow's colostrum (the first milk) could help prevent recurring urinary tract infections (UTIs) in children. Sixty children with a history of frequent UTIs were randomly assigned to take either the colostrum supplement or a pla…

This study tested a new oral drug, MMV367, for malaria. Researchers gave healthy volunteers a small, controlled dose of malaria parasites and then gave them the drug to see how their bodies processed it and how well it fought the infection. The main goal was to understand the rel…

This study investigated whether people who run ultramarathons get more infections like colds and sore throats in the weeks after a race. Researchers compared 471 ultramarathon runners with their non-running companions who lived in the same home. They tracked symptoms for 21 days …