INFECTIONS

This study follows healthy pregnant women who previously received an experimental Group B Streptococcus (GBS) vaccine to see if their immune protection lasts. It also tests whether a booster dose given during a new pregnancy is safe and boosts immunity, aiming to protect newborns…

This study looks at whether treating people with conditions like heart failure, infections, or diabetes at home (instead of in the hospital) can lead to better health and happier patients. About 9,600 adults will take part, receiving hospital-level care in their own homes. Resear…

This study tests whether infant formula with added bio-active ingredients helps healthy babies grow well and have fewer infections compared to standard formula. About 456 full-term, healthy infants will be enrolled and followed for several months. Parents will report any infectio…

This study tests if bevacizumab, a drug that blocks blood vessel growth, can help adults with recurrent respiratory papillomatosis (RRP) go longer between surgeries. RRP causes wart-like growths in the airways that often return after removal. About 21 participants will receive th…

This study looks at 800 children with mild open fractures to see if a single dose of antibiotics works as well as longer treatments to prevent infections. Participants will receive either one dose, 24 hours, or 24 hours plus 5 days of oral antibiotics. The goal is to find the saf…

This study re-infects healthy adults who previously had a mild bird flu (H10N7) with the same virus. The goal is to understand how the body fights off repeat infections, which can help design better flu vaccines. Participants stay in the hospital for at least 9 days and provide s…

This study looks at whether taking vitamin D and omega-3 (fish oil) supplements can lower the risk of infections like colds, flu, and urinary tract infections in healthy adults. It involves over 25,000 participants from a larger heart and cancer study. The goal is to understand h…

This study tests a new digital platform that helps hospitals share patient information more reliably when a patient is transferred from one hospital to another. About 1,000 adults being moved to Brigham and Women's Hospital from three other hospitals will take part. The goal is t…

This study looks at how social factors like poverty and access to care affect the risk of maternal sepsis—a leading cause of death in new mothers. Researchers will interview 200 patients and community stakeholders in New York hospitals to gather their experiences and ideas. The g…

This study is observing over 2,000 people and their pets in the Canton of Bern, Switzerland, to understand how infections like COVID-19 spread and how social and environmental factors affect transmission. Participants provide nasal swabs, blood samples, and answer questionnaires …

This study planned to see if an artificial intelligence system could predict sepsis—a dangerous infection—in people recovering from abdominal surgery. Participants would have worn a simple, non-invasive device to track vital signs, and the AI would combine that data with medical …

This study looks at the health records of 400,000 birthing people to find better ways to predict and prevent maternal sepsis, a leading cause of death during and after childbirth. It focuses on understanding how social factors like poverty and race affect risk, especially for Bla…