HYPERTENSION (HTN)

This study tests whether a new fixed-dose combination of two drugs (torsemide and spironolactone) works better than the current drug finerenone for people with both high blood pressure and chronic kidney disease. About 30 adults with moderate to severe kidney disease and high blo…

This study looks at how well CPAP therapy lowers blood pressure in people with obstructive sleep apnea and high blood pressure. Researchers will also test if adding a low-dose sleep aid (trazodone or zolpidem) for those with insomnia helps even more. About 200 adults aged 18–70 w…

This study looks at whether trained female community health volunteers can help people in Nepal better manage high blood pressure and diabetes. About 400 adults aged 30 and older with these conditions will take part. The health workers will provide education, monitor blood pressu…

This study aims to help people with uncontrolled high blood pressure (above 150/95) get their numbers down. It uses a team of doctors, pharmacists, and nurses who work with patients to adjust medications based on home blood pressure readings. About 1,520 adults aged 18-85 will ta…

This study compares a wearable blood pressure monitor (Aktiia G1) to a traditional arm cuff in adults with high blood pressure. Over 6 months, researchers will see which method helps lower blood pressure more effectively. Participants must have uncontrolled hypertension and own a…

This study tests whether combining mild electrical nerve stimulation (TENS) with isometric exercise can improve blood pressure in people with resistant hypertension—high blood pressure that doesn't respond to multiple medications. Fifty men and women aged 50 to 60 will be split i…

This study looks at whether adding a community health worker coach to remote blood pressure monitoring helps women who had high blood pressure during pregnancy better control their blood pressure and improve heart health after giving birth. About 240 women will be enrolled and fo…

This study is a French registry that will follow 100 adults with high blood pressure who undergo a procedure called renal denervation, which uses radiofrequency or ultrasound to calm overactive kidney nerves. The goal is to see how much blood pressure drops one year after the pro…

This study looks at whether adding a special breathing technique (alternate nostril breathing) to aerobic interval training helps lower blood pressure and improve heart function more than exercise alone. It involves 36 adults aged 25–50 with stage 1 or 2 hypertension. Participant…

This study tests if doing wall squats at home, along with healthy lifestyle advice, is a practical way for people with high blood pressure to manage their condition. Seventy adults with hypertension will do the exercise three times a week for 12 weeks, guided remotely by a traine…

This study compares two types of exercise—short, intense bursts (SIT) versus steady, moderate activity (MICT)—to see which is better at lowering blood pressure in adults aged 30-59 with hypertension. Over 12 weeks, 20 participants will do supervised workouts three times a week. T…

This study checks if a chest-patch that measures blood pressure without a cuff is as accurate as the standard arm-cuff method over 24 hours. About 600 adults with or without high blood pressure will wear both devices. The goal is to see if the patch is reliable and easier to use.

This study looks at whether very short exercise sessions (5-10 minutes) can help lower blood pressure in people with hypertension. Researchers will measure blood pressure over 24 hours and check artery health. The study needs 45 adults aged 18-55 who are not on blood pressure med…

This study looks at whether a beetroot supplement can help older women (ages 60-70) with high blood pressure during exercise. Researchers will measure blood pressure, muscle oxygen, and stress markers after taking the extract and doing aerobic exercise. The goal is to see if beet…

This study looks at whether high levels of homocysteine (a substance in the blood) are linked to early signs of heart stiffness in people recently diagnosed with high blood pressure. Researchers will compare heart ultrasound results between those with normal and high homocysteine…

This study will use wearable digital patches to collect heart data from 5,000 adults with conditions like heart failure, high blood pressure, and heart valve disease. The goal is to observe how these conditions change over time for research purposes. Participants wear a sensor pa…

This study looks at how not eating enough calories to match intense training—called low energy availability—may affect the heart health of Black Division I athletes at HBCUs. Researchers will measure blood vessel stiffness, blood sugar, and cholesterol in 150 athletes aged 18-25.…

This study looks at how well adults with chronic conditions like inflammatory bowel disease, high blood pressure, anemia, or multiple sclerosis accept and stick with two dietary supplements (Goodphyte IB Defense and Goodphyte Immunity). The supplements contain a natural enzyme th…